Atypical teratoid rhabdoid tumor surgery: Difference between revisions
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*Surgery plays a critical role in obtaining [[Tissue (biology)|tissue]] to make an accurate [[diagnosis]]. Surgery alone is not curative. | *Surgery plays a critical role in obtaining [[Tissue (biology)|tissue]] to make an accurate [[diagnosis]]. Surgery alone is not curative. | ||
*In addition, 30% of the atypical teratoid rhabdoid tumors are located supratentorially and there is a predilection for the cerebello-pontine angle, which makes surgical resection difficult. One-third or more children will have [[disseminated disease]] at the time of diagnosis. Total or near-total resections are often not possible.<ref>[http://www.utmb.edu/otoref/Grnds/Mass-CPA-040602/Mass-CPA-slides-040602.pdf PDF</ref> | *In addition, 30% of the atypical teratoid rhabdoid tumors are located supratentorially and there is a predilection for the cerebello-pontine angle, which makes surgical resection difficult. One-third or more children will have [[disseminated disease]] at the time of diagnosis. Total or near-total resections are often not possible.<ref>[http://www.utmb.edu/otoref/Grnds/Mass-CPA-040602/Mass-CPA-slides-040602.pdf PDF</ref> | ||
==Stem Cell Transplantation== | |||
*Stem cell transplantation is indicated in very aggressive atypical teratoid rhabdoid tumors, to receive high doses of chemotherapy. | |||
==References== | ==References== | ||
Revision as of 15:56, 21 December 2015
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Atypical teratoid rhabdoid tumor Microchapters |
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Differentiating Atypical Teratoid Rhabdoid Tumor from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Surgery plays a critical role in obtaining tissue to make an accurate diagnosis. Surgery alone is not curative. In addition, 30% of the AT/RTs are located supratentorially and there is a predilection for the cerebello-pontine angle[1] which makes surgical resection difficult. One-third or more children will have disseminated disease at the time of diagnosis. Total or near-total resections are often not possible.
Surgery
- Surgery is the mainstay of treatment for atypical teratoid rhabdoid tumor.[2]
- Surgery plays a critical role in obtaining tissue to make an accurate diagnosis. Surgery alone is not curative.
- In addition, 30% of the atypical teratoid rhabdoid tumors are located supratentorially and there is a predilection for the cerebello-pontine angle, which makes surgical resection difficult. One-third or more children will have disseminated disease at the time of diagnosis. Total or near-total resections are often not possible.[3]
Stem Cell Transplantation
- Stem cell transplantation is indicated in very aggressive atypical teratoid rhabdoid tumors, to receive high doses of chemotherapy.
References
- ↑ [http://www.utmb.edu/otoref/Grnds/Mass-CPA-040602/Mass-CPA-slides-040602.pdf PDF
- ↑ Ginn, Kevin F.; Gajjar, Amar (2012). "Atypical Teratoid Rhabdoid Tumor: Current Therapy and Future Directions". Frontiers in Oncology. 2. doi:10.3389/fonc.2012.00114. ISSN 2234-943X.
- ↑ [http://www.utmb.edu/otoref/Grnds/Mass-CPA-040602/Mass-CPA-slides-040602.pdf PDF