Parathyroid cancer medical therapy: Difference between revisions
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There are different types of treatment for patients with parathyroid cancer. | There are different types of treatment for patients with parathyroid cancer. | ||
Treatment includes control of hypercalcemia (too much calcium in the blood) in patients who have an overactive parathyroid gland. | Treatment includes control of hypercalcemia (too much calcium in the blood) in patients who have an overactive parathyroid gland. | ||
* Conventional treatment with intravenous fluids, diuretics, and antiresorptive agents such as biphosphonates, gallium, or mithramycin may help control the hypercalcemia. Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands may offer an important new approach to medical therapy of primary HPT associated with parathyroid cancer. | |||
Four types of standard treatment are used: | Four types of standard treatment are used: | ||
Surgery | Surgery | ||
Revision as of 16:12, 22 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Medical Therapy
There are different types of treatment for patients with parathyroid cancer. Treatment includes control of hypercalcemia (too much calcium in the blood) in patients who have an overactive parathyroid gland.
- Conventional treatment with intravenous fluids, diuretics, and antiresorptive agents such as biphosphonates, gallium, or mithramycin may help control the hypercalcemia. Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands may offer an important new approach to medical therapy of primary HPT associated with parathyroid cancer.
Four types of standard treatment are used: Surgery Radiation therapy Chemotherapy Supportive care Follow-up tests may be needed.
- Gallium nitrate is used to reduce the calcium levels.
- Calcitonin is used to control the calcium levels
Radiation therapy
Radiation therapy is a cancer treatment that uses high-energy x-rays or other types of radiation to kill cancer cells or stop them from growing. There are two types of radiation therapy. External radiation therapy uses a machine outside the body to send radiation toward the cancer. Internal rad iation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer. The way the radiation therapy is given depends on the type and stage of the cancer being treated.
Chemotherapy
Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.
Supportive care
Supportive care is given to lessen the problems caused by the disease or its treatment. Supportive care for hypercalcemia caused by parathyroid cancer may include the following:
Intravenous (IV) fluids. Drugs that increase how much urine the body makes. Drugs that stop the body from absorbing calcium from the food we eat. Drugs that stop the parathyroid gland from making parathyroid hormone.