Neuroblastoma physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

A positive finding of a palpable abdominal mass, fever, and purple skin patches is suggestive of neuroblastoma.

Physical Examination

General Appearance

• Neuroblastoma patients often appear fatigued

Vital Signs

• Fever
• Elevated blood pressure
• Tachycardia

Skin

• Pallor may be present
• Ecchymoses may be present
• Purple skin patches may be present
• Subcutaneous nodules may be present

HEENT

• Periorbital ecchymosis may be present
• Visual defects may be present
• Conjuctival pallor may be present
• Nystagmus may be present
• Proptosis may be present
• Ptosis may be present
• Miosis may be present
• Anhidrosis may be present

Abdomen

• Abdominal mass may be palpated

Skeletal

• Sudden muscle jerks may be present
• Bone tenderness may be present

CNS

• Motor weakness may be present
• Sensory loss may be present
• Paralysis may be present
• Ataxia may be present