Aspergillosis laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Aspergillosis}} | {{Aspergillosis}} | ||
{{CMG}}; {{AE}} {{HL}} | {{CMG}}; {{AE}} {{HL}}; {{YD}}; {{SSK}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of aspergillosis include positive aspergillus antibody test, positive [[galactomannan]] test, and elevated concentration of [[IgE]] [[immunoglobulin]].<ref name="wiki">Aspergillosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Aspergillosis#Diagnosis Accessed on February, 8 2016</ref><ref name="pmid21177400">{{cite journal| author=Cuenca-Estrella M, Bassetti M, Lass-Flörl C, Rácil Z, Richardson M, Rogers TR| title=Detection and investigation of invasive mould disease. | journal=J Antimicrob Chemother | year= 2011 | volume= 66 Suppl 1 | issue= | pages= i15-24 | pmid=21177400 | doi=10.1093/jac/dkq438 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21177400 }} </ref><ref name="pmid18384212">{{cite journal| author=Kradin RL, Mark EJ| title=The pathology of pulmonary disorders due to Aspergillus spp. | journal=Arch Pathol Lab Med | year= 2008 | volume= 132 | issue= 4 | pages= 606-14 | pmid=18384212 | doi=10.1043/1543-2165(2008)132[606:TPOPDD]2.0.CO;2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18384212 }} </ref> | Laboratory findings consistent with the diagnosis of aspergillosis include positive aspergillus antibody test, positive [[galactomannan]] test, and elevated concentration of [[IgE]] [[immunoglobulin]].<ref name="wiki">Aspergillosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Aspergillosis#Diagnosis Accessed on February, 8 2016</ref><ref name="pmid21177400">{{cite journal| author=Cuenca-Estrella M, Bassetti M, Lass-Flörl C, Rácil Z, Richardson M, Rogers TR| title=Detection and investigation of invasive mould disease. | journal=J Antimicrob Chemother | year= 2011 | volume= 66 Suppl 1 | issue= | pages= i15-24 | pmid=21177400 | doi=10.1093/jac/dkq438 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21177400 }} </ref><ref name="pmid18384212">{{cite journal| author=Kradin RL, Mark EJ| title=The pathology of pulmonary disorders due to Aspergillus spp. | journal=Arch Pathol Lab Med | year= 2008 | volume= 132 | issue= 4 | pages= 606-14 | pmid=18384212 | doi=10.1043/1543-2165(2008)132[606:TPOPDD]2.0.CO;2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18384212 }} </ref> | ||
Revision as of 22:50, 8 February 2016
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Aspergillosis Microchapters |
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Aspergillosis laboratory findings On the Web |
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Risk calculators and risk factors for Aspergillosis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Yazan Daaboul, M.D.; Serge Korjian M.D.
Overview
Laboratory findings consistent with the diagnosis of aspergillosis include positive aspergillus antibody test, positive galactomannan test, and elevated concentration of IgE immunoglobulin.[1][2][3]
Laboratory Findings
Complete Blood Count
Electrophoresis
- Elevated concentration of serum immunoglobulin E (IgE)
Biomarkers
- Positive galactomannan assay
- Positive beta-D-glucan assay
Culture
- Positive sputum culture and stain following bronchoalveolar lavage (BAL)
- Can be done on a variety of sterile specimens and Aspergillus spp. present as rapidly growing molds that are visible 1-3 days after incubation.
- However, patients with invasive aspergillosis may have negative cultures.
References
- ↑ Aspergillosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Aspergillosis#Diagnosis Accessed on February, 8 2016
- ↑ Cuenca-Estrella M, Bassetti M, Lass-Flörl C, Rácil Z, Richardson M, Rogers TR (2011). "Detection and investigation of invasive mould disease". J Antimicrob Chemother. 66 Suppl 1: i15–24. doi:10.1093/jac/dkq438. PMID 21177400.
- ↑ Kradin RL, Mark EJ (2008). "The pathology of pulmonary disorders due to Aspergillus spp". Arch Pathol Lab Med. 132 (4): 606–14. doi:10.1043/1543-2165(2008)132[606:TPOPDD]2.0.CO;2. PMID 18384212.
de:Aspergillose hr:Aspergiloza nl:Aspergillose uk:Аспергільоз } Template:WH Template:WS