Differentiating ankylosing spondylitis from other diseases: Difference between revisions
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*[[Rheumatoid arthritis]] | *[[Rheumatoid arthritis]] | ||
*[[Bone cancer]] | *[[Bone cancer]] | ||
{| class="wikitable" | |||
!Disease | |||
!Differentiating signs and symptoms | |||
!Diagnostic findings | |||
|- | |||
|[[Fibromyalgia]] | |||
| | |||
* Symptoms have been present at a similar level for at least 3 months. | |||
* Chronic [[musculoskeletal pain]] with multiple tender points | |||
* [[Stiffness]], [[numbness]], and [[fatigue]] | |||
* [[Headaches]] | |||
* [[Sleep disorder]] | |||
| | |||
*All lab tests are normal | |||
|- | |||
|[[Rheumatoid arthritis]] | |||
| | |||
* Multiple [[joint swelling]] | |||
* Morning [[stiffness]] | |||
* [[Rheumatoid nodules]] | |||
| | |||
* [[Rheumatoid factor|RF]] or [[Anti-citrullinated protein antibody|anti-cyclic citrullinated protein (CCP) antibody]] is positive. | |||
* Markers of systemic inflammation ([[ESR]], [[CRP]]) are typically elevated. | |||
|- | |||
|[[SLE]] | |||
| | |||
* [[Maculopapular rash]] | |||
* Multi-system involvement | |||
| | |||
*Positive anti-Smith [[antibodies]] | |||
|- | |||
|[[Chronic fatigue syndrome]] | |||
|Fatigue plus 4 of the following symptoms: | |||
*Short-term [[memory loss]] | |||
*[[Sore throat]] | |||
*Tender [[lymph nodes]] in the neck or armpit | |||
*[[Muscle pain]] | |||
*[[Joint pain]] without [[swelling]] or [[Redness of the skin|redness]] | |||
*[[Headaches]] | |||
*[[Insomnia]] | |||
*[[Malaise]] | |||
| | |||
*Diagnosis of exclusions | |||
*Symptoms must present for more than 6 months | |||
|- | |||
|[[Spondyloarthritis]] | |||
| | |||
* [[Axial skeleton|Axial skeletal]] pain and [[stiffness]] | |||
* Restricted spinal motion | |||
| | |||
* Elevated [[ESR]] or [[CRP]] | |||
* Negative [[RF]] | |||
* [[Bamboo spine]] on [[x-ray]] | |||
|- | |||
|[[Polymyalgia rheumatica]] | |||
| | |||
* Older at onset | |||
* Generalized [[stiffness]] | |||
| | |||
* An elevated [[erythrocyte sedimentation rate]] ([[ESR]]) OR [[C-reactive protein]] (CRP) | |||
* Response to [[corticosteroids]] | |||
|- | |||
|[[Osteoarthritis]] | |||
| | |||
* Localized [[joint pain]] | |||
* Restricted to affect joints | |||
* Older at onset | |||
| | |||
* [[X-ray]] of the involved joints demonstrate degenerative changes | |||
|- | |||
|[[Hypothyroidism]] | |||
| | |||
*Systemic symptoms such as [[weight gain]], [[constipation]], [[dry skin]] | |||
*[[Myalgia|Muscular aching]] and prominent [[fatigue]] that improves on replacement of [[thyroid hormone]]. | |||
| | |||
*[[TSH]] is elevated and free [[T4]] is low. | |||
|- | |||
|Myopathaies ([[polymyositis]] and [[dermatomyositis]]) | |||
| | |||
*Pelvic and shoulder girdle [[muscle weakness]] | |||
*[[Rash]] | |||
| | |||
*[[Muscle biopsy]] confirms the diagnosis | |||
*Elevated [[CPK|CPK enzyme]] | |||
|- | |||
|[[Neuropathy]] | |||
| | |||
*[[Numbness]] and [[tingling]] | |||
*[[Paresthesia]] | |||
| | |||
*Abnormal [[EMG]] | |||
|} | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Latest revision as of 18:42, 14 August 2017
Ankylosing spondylitis Microchapters |
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Risk calculators and risk factors for Differentiating ankylosing spondylitis from other diseases |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ankylosing spondylitis needs to be differentiated from certain conditions such as a strain of the lumbosacral joint, osteoarthritis, and Forestier's disease.
Differentiating Ankylosing spondylitis from other Diseases
Diseases that can have similar symptoms are
- Strain of lumbosacral joint
- Osteoarthritis
- Forestier's disease
- Tuberculous spondylitis
- Rheumatoid arthritis
- Bone cancer
Disease | Differentiating signs and symptoms | Diagnostic findings |
---|---|---|
Fibromyalgia |
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|
Rheumatoid arthritis |
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|
SLE |
|
|
Chronic fatigue syndrome | Fatigue plus 4 of the following symptoms:
|
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Spondyloarthritis |
|
|
Polymyalgia rheumatica |
|
|
Osteoarthritis |
|
|
Hypothyroidism |
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|
Myopathaies (polymyositis and dermatomyositis) |
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Neuropathy |
|