Acute liver failure history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
===History === | ===History === | ||
History | Obtaining the focused history is an important aspect of making a diagnosis of an acute liver failure. It provides insight into the cause, precipitating factors and associated comorbid conditions. The complete history will help determine the correct therapy and helps in determining the prognosis. Encephalopathy patients are disoriented therefore the patient interview may be difficult. In such cases, history from the family members may need to be obtained. Specific histories about the symptoms (duration, onset, progression), associated symptoms, drug usage have to be obtained. Specific areas of focus when obtaining the history are: | ||
* Timing of onset of jaundice and other symptoms (malaise, nausea, vomiting or mental status changes) | |||
* History of alcohol use | |||
* Medications intake (prescription, illicit, herbal or recreational) use (prescription and illicit or recreational) | |||
* Family history of liver disease (Wilson disease) | |||
* Viral hepatitis risks (sexual contact, transfusions, travel, occupational, body piercing) | |||
* Hepatic toxins exposure (organic solvents, mushroom poisoning) | |||
* History of renal failure, seizures, bleeding, infection | |||
* Past history of jaundice | |||
* Risk factors of drug overdose (acetaminophen) such as prior history of suicide attempt, depression etc | |||
* Risk factors for hepatic ischemia such has hypotension, heart failure, hypercoagulable state | |||
===Symptoms=== | ===Symptoms=== | ||
Revision as of 20:28, 6 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
A thorough history should be obtained, with special attention given to a history of ingesting medications or other toxins. Symptoms can include symptoms such as fatigue, nausea, vomiting, abdominal distention, diarrhea, disorientation, and an increased bleeding tendency.
History and Symptoms
History
Obtaining the focused history is an important aspect of making a diagnosis of an acute liver failure. It provides insight into the cause, precipitating factors and associated comorbid conditions. The complete history will help determine the correct therapy and helps in determining the prognosis. Encephalopathy patients are disoriented therefore the patient interview may be difficult. In such cases, history from the family members may need to be obtained. Specific histories about the symptoms (duration, onset, progression), associated symptoms, drug usage have to be obtained. Specific areas of focus when obtaining the history are:
- Timing of onset of jaundice and other symptoms (malaise, nausea, vomiting or mental status changes)
- History of alcohol use
- Medications intake (prescription, illicit, herbal or recreational) use (prescription and illicit or recreational)
- Family history of liver disease (Wilson disease)
- Viral hepatitis risks (sexual contact, transfusions, travel, occupational, body piercing)
- Hepatic toxins exposure (organic solvents, mushroom poisoning)
- History of renal failure, seizures, bleeding, infection
- Past history of jaundice
- Risk factors of drug overdose (acetaminophen) such as prior history of suicide attempt, depression etc
- Risk factors for hepatic ischemia such has hypotension, heart failure, hypercoagulable state
Symptoms
- Nausea or vomiting
- Loss of appetite
- Fatigue
- Diarrhea
- Jaundice
- Bleeding easily
- Abdominal distention
- Disorientation or confusion
- Sleepiness, even coma