Necrotizing fasciitis laboratory findings: Difference between revisions
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===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ||
LRINEC scoring is used to distinguish necrotizing fasciitis from other soft tissue infections.<ref name="pmid15241098">{{cite journal| author=Wong CH, Khin LW, Heng KS, Tan KC, Low CO| title=The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. | journal=Crit Care Med | year= 2004 | volume= 32 | issue= 7 | pages= 1535-41 | pmid=15241098 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15241098 }} </ref> | |||
==References== | ==References== | ||
Revision as of 14:51, 8 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Laboratory Findings
Laboratory tests consistent with diagnosis of necrotizing fasciitis include:
Microbiology
The following are the tests used to diagnose the causative organism:
- Gram stain and culture of tissues and aspirates
- Blood culture
- Culture of throat and vaginal swabs
- Fungal culture (immunocompromised or trauma patients)
- Enrichment cultures (patients with recent antibiotic use)
Haematology
The following are complete blood count with differential findings:
- Rapidly falling heamoglobin
- Leucocytosis (>14,000/µL)
- Leucopenia (if associated with STSS)
- Lymphopenia
- Thrombocytopenia
Boichemistry
The biochemistry findings consistent with diagnosis of necrotizing fasciitis include:
- Elevated C-reactive protein
- Elevated serum creatinine kinase
- Hypocalcemia (sign of severity in synergistic NF)
- Hypoalbuminemia
- Hyponatremia (<135mmol/L)
- Elevated serum lactate levels (high serum lactate combined with low sodium levels may be predictive of mortality)
- Arterial blood gas analysis
- Urine analysis
- Elevated Blood urea nitrogen (BUN)
Biopsy
- Deep incisional biopsy (include advancing edge and central necrotic areas)
Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system
LRINEC scoring is used to distinguish necrotizing fasciitis from other soft tissue infections.[1]
References
- ↑ Wong CH, Khin LW, Heng KS, Tan KC, Low CO (2004). "The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections". Crit Care Med. 32 (7): 1535–41. PMID 15241098.