Necrotizing fasciitis laboratory findings: Difference between revisions
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===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ===Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system=== | ||
*LRINEC scoring | *LRINEC is a dignostic scoring system used to distinguish necrotizing fasciitis from other soft tissue infections.<ref name="pmid15241098">{{cite journal| author=Wong CH, Khin LW, Heng KS, Tan KC, Low CO| title=The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. | journal=Crit Care Med | year= 2004 | volume= 32 | issue= 7 | pages= 1535-41 | pmid=15241098 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15241098 }} </ref> | ||
*It was first established by by Wong et al in 2004. | *It was first established by by Wong et al in 2004. | ||
* | * | ||
Revision as of 15:53, 8 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Laboratory Findings
Laboratory tests consistent with diagnosis of necrotizing fasciitis include:
Microbiology
The following are the tests used to diagnose the causative organism:
- Gram stain and culture of tissues and aspirates
- Blood culture
- Culture of throat and vaginal swabs
- Fungal culture (immunocompromised or trauma patients)
- Enrichment cultures (patients with recent antibiotic use)
Hematology
The following are complete blood count with differential findings:
- Rapidly falling heamoglobin
- Leucocytosis (>14,000/µL)
- Leucopenia (if associated with STSS)
- Lymphopenia
- Thrombocytopenia
Boichemistry
The biochemistry findings consistent with diagnosis of necrotizing fasciitis include:
- Elevated C-reactive protein
- Elevated serum creatinine kinase
- Hypocalcemia (sign of severity in synergistic NF)
- Hypoalbuminemia
- Hyponatremia (<135mmol/L)
- Elevated serum lactate levels (high serum lactate combined with low sodium levels may be predictive of mortality)
- Arterial blood gas analysis
- Urine analysis
- Elevated Blood urea nitrogen (BUN)
Biopsy
- Deep incisional biopsy (include advancing edge and central necrotic areas)
Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system
- LRINEC is a dignostic scoring system used to distinguish necrotizing fasciitis from other soft tissue infections.[1]
- It was first established by by Wong et al in 2004.
References
- ↑ Wong CH, Khin LW, Heng KS, Tan KC, Low CO (2004). "The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections". Crit Care Med. 32 (7): 1535–41. PMID 15241098.