Zika virus infection epidemiology and demographics: Difference between revisions
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| style="background: #DCDCDC; padding: 5px;" | Raised white cell count but <15,000 cells/mL and serum creatine <nowiki><1.5 times baseline</nowiki> | | style="background: #DCDCDC; padding: 5px;" | Raised white cell count but <15,000 cells/mL and serum creatine <nowiki><1.5 times baseline</nowiki> | ||
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Revision as of 01:22, 16 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Luke Rusowicz-Orazem, B.S.; Serge Korjian M.D.
Overview
In 2015, Zika virus infection outbreaks rose dramatically, particularly in Brazil as observed by the manifestation of a correlated complication, microcephaly, in infants born to mothers with Zika virus infection, an incidence of approximately 100 per 100,000 infants. The majority of Zika virus infection cases are reported in South Africa and Tropical Asia. As of 2014, Zika Virus infection outbreaks have also become more common in South America. Cases reported in other regions of the world are attributed to travel from areas with outbreaks. Zika virus infection affects all age groups, with newborn infants particularly vulnerable due to risk of transmission from the mothers upon birth.
Epidemiology and Demographics
U.S. Reported Cases
There have been no cases of local viral transmission in the continental United States. All the cases reported have been due to travel to endemic regions in South or Central America. The interactive map below shows the number of cases reported in the United States for the 2015-2016 outbreak. The table below excludes cases that have been diagnosed in 2014.
Americas
According to Pan American Health Organisation (WHO regional office for Americas), 46 countries and territories have confirmed indigenous vector-borne transmission of Zika virus in the region of Americas since 2015(most recent update September 8, 2016).
| North America | Central America | Caribbean | South America |
|---|---|---|---|
| Mild | Diarrhea as the only symptom | Moderate | Raised white cell count but <15,000 cells/mL and serum creatine <1.5 times baseline |
Incidence
- As only 1 in 5 people with Zika virus usually becomes symptomatic, and given that the symptoms are generally mild, it is hard to establish a clear incidence of the infection.
- The incidence of Zika virus infection is often correlated to the one of its circumstantially associated complications: microcephaly
- Based on this method, the incidence of Zika virus infection in increasing.
- As of November 2015, it is estimated that 99.7/100,000 live births of infants displaying microcephaly could be attributed to Zika virus.
- This is a twentyfold increase from 2010's report of 5.7/100,000 cases.[1]
Age
Gender
- Men and women are equally affected by Zika virus infection.
Countries
- While Zika virus infection outbreaks have not been reported in developed countries, cases have been reported in travelers returning from affected countries.[3]
- No autochthonous cases of Zika virus infection have been reported in Europe or the United States.[4]
- Before 2007, Zika virus infection outbreaks reports were limited to Tropical Africa and Southeast Asia. However, an outbreak on Yap Island in the Federated States of Micronesia in 2007 was the first of several cases reported on Pacific islands and archipelagos outside of Africa and Asia.[5]
- Zika virus infection outbreaks have mainly been reported in Mexico and South America.[5]
- The first South American outbreak was reported originating in Easter Island, Chile, in 2014.
- Countries with local Zika virus transmission in 2015-2016 outbreak include:[1]
- American Samoa
- Aruba
- Barbados
- Bolivia
- Bonaire
- Brazil
- Cabo Verde
- Colombia
- Costa Rica
- Curacao
- Dominican Republic
- Ecuador
- El Salvador
- French Guiana
- Guadeloupe (France)
- Guatemala
- Guyana
- Haiti
- Honduras
- Jamaica
- Marshall Islands
- Martinique (France)
- Mexico
- New Caledonia
- Nicaragua
- Panama
- Paraguay
- Puerto Rico
- Saint Martin (France)
- Samoa
- Sint Maarten
- Saint Vincent and the Grenadines
- Suriname
- Thailand
- The Commonwealth of Puerto Rico, a U.S. territory
- Tonga
- Trinidad and Tobago
- Venezuela
- Virgin Islands (U.S.)
References
- ↑ 1.0 1.1 1.2 "Epidemiological Alert: Neurological Syndromes, Congenital Malformations, and Zika Virus Infection. Implications for Public Health in the Americas". Pan American Health Organization. Pan American Health Organization. December 1, 2015. Retrieved December 11, 2015.
- ↑ "Zika Virus: Geographical Distribution". CIDRAP Center for Infectious Disease Research and Policy. University of Minnesota. December 1, 2015. Retrieved December 14, 2015.
- ↑ Schnirring, Lisa (December 11, 2015). "PAHO Issues Zika Virus Alert". CDC.Gov. Center for Disease Control. Retrieved December 14, 2015.
- ↑ Epidemiological update: Outbreaks of Zika virus and complications potentially linked to the Zika virus infection. ECDC (2016). http://ecdc.europa.eu/en/press/news/_layouts/forms/News_DispForm.aspx?ID=1342&List=8db7286c-fe2d-476c-9133-18ff4cb1b568&Source=http%3A%2F%2Fecdc%2Eeuropa%2Eeu%2Fen%2Fhealthtopics%2Fzika%5Fvirus%5Finfection%2FPages%2Findex%2Easpx#sthash.vy0uYach.dpuf. Accessed on January 25, 2016.
- ↑ 5.0 5.1 "Zika Virus Infection Factsheet for Health Professionals". European Centre for Disease Prevention and Control. November 11, 2015. Retrieved December 11, 2015.
- ↑ Hennessey M, Fischer M, Staples JE. Zika Virus Spreads to New Areas — Region of the Americas, May 2015–January 2016. MMWR Morb Mortal Wkly Rep 2016;65:55–58. DOI: http://dx.doi.org/10.15585/mmwr.mm6503e1