Focal segmental glomerulosclerosis overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Focal segmental glomerulosclerosis''' (FSGS) is a cause of [[nephrotic syndrome]] in children and adolescents, as well as an important cause of [[kidney failure]] in adults.<ref name=Robbins_2005>{{cite book | author = Kumar V, Fausto N, Abbas A (editors) | title = Robbins & Cotran Pathologic Basis of Disease | edition = 7th | pages= pp. 982-3 | publisher = Saunders | year = 2003 | id = ISBN 978-0-721-60187-8 }}</ref> [[Minimal change disease]] (MCD) is by far the most common cause of nephrotic syndrome in children: MCD and primary FSGS may have a similar cause.<ref name=Robbins_2005 /> | '''Focal segmental glomerulosclerosis''' (FSGS) is a cause of [[nephrotic syndrome]] in children and adolescents, as well as an important cause of [[kidney failure]] in adults.<ref name=Robbins_2005>{{cite book | author = Kumar V, Fausto N, Abbas A (editors) | title = Robbins & Cotran Pathologic Basis of Disease | edition = 7th | pages= pp. 982-3 | publisher = Saunders | year = 2003 | id = ISBN 978-0-721-60187-8 }}</ref> Focal Segmental Glomerulosclerosis (FSGS) is a distinct finding and a descriptive report on the glomerular morphology seen in certain glomerular disease conditions. It is considered to be a glomerular podocytopathy <ref name="pmidPMID: 24589721">{{cite journal| author=Sethi S, Glassock RJ, Fervenza FC| title=Focal segmental glomerulosclerosis: towards a better understanding for the practicing nephrologist. | journal=Nephrol Dial Transplant | year= 2015 | volume= 30 | issue= 3 | pages= 375-84 | pmid=PMID: 24589721 | doi=10.1093/ndt/gfu035 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24589721 }} </ref>. [[Minimal change disease]] (MCD) is by far the most common cause of nephrotic syndrome in children: MCD and primary FSGS may have a similar cause.<ref name=Robbins_2005 /> | ||
The individual components of the name refer to the appearance of the kidney tissue on [[biopsy]]: ''focal'' - only some of the [[glomerulus|glomeruli]] are involved (as opposed to diffuse), ''segmental'' - only part of an entire glomerulus is involved (as opposed to global), ''glomerulosclerosis'' - refers to scarring of the [[glomerulus]] (a part of the [[nephron]] (the functional unit of the [[kidney]])). | The individual components of the name refer to the appearance of the kidney tissue on [[biopsy]]: ''focal'' - only some of the [[glomerulus|glomeruli]] are involved (as opposed to diffuse), ''segmental'' - only part of an entire glomerulus is involved (as opposed to global), ''glomerulosclerosis'' - refers to scarring of the [[glomerulus]] (a part of the [[nephron]] (the functional unit of the [[kidney]])). | ||
Revision as of 15:30, 18 October 2016
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Focal segmental glomerulosclerosis Microchapters |
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Differentiating Focal segmental glomerulosclerosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief:’’’ Cafer Zorkun, M.D., Ph.D. [2]Olufunmilola Olubukola M.D.[3]
Overview
Focal segmental glomerulosclerosis (FSGS) is a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults.[1] Focal Segmental Glomerulosclerosis (FSGS) is a distinct finding and a descriptive report on the glomerular morphology seen in certain glomerular disease conditions. It is considered to be a glomerular podocytopathy [2]. Minimal change disease (MCD) is by far the most common cause of nephrotic syndrome in children: MCD and primary FSGS may have a similar cause.[1]
The individual components of the name refer to the appearance of the kidney tissue on biopsy: focal - only some of the glomeruli are involved (as opposed to diffuse), segmental - only part of an entire glomerulus is involved (as opposed to global), glomerulosclerosis - refers to scarring of the glomerulus (a part of the nephron (the functional unit of the kidney)).
References
- ↑ 1.0 1.1 Kumar V, Fausto N, Abbas A (editors) (2003). Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. pp. pp. 982-3. ISBN 978-0-721-60187-8.
- ↑ Sethi S, Glassock RJ, Fervenza FC (2015). "Focal segmental glomerulosclerosis: towards a better understanding for the practicing nephrologist". Nephrol Dial Transplant. 30 (3): 375–84. doi:10.1093/ndt/gfu035. PMID 24589721 PMID: 24589721 Check
|pmid=value (help).