Amoebic liver abscess pathophysiology: Difference between revisions
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*The [[infection]] is transmitted to [[liver]] by [[portal venous system]].<ref name="pmid473308">{{cite journal |vauthors=Aikat BK, Bhusnurmath SR, Pal AK, Chhuttani PN, Datta DV |title=The pathology and pathogenesis of fatal hepatic amoebiasis--A study based on 79 autopsy cases |journal=Trans. R. Soc. Trop. Med. Hyg. |volume=73 |issue=2 |pages=188–92 |year=1979 |pmid=473308 |doi= |url=}}</ref> | *The [[infection]] is transmitted to [[liver]] by [[portal venous system]].<ref name="pmid473308">{{cite journal |vauthors=Aikat BK, Bhusnurmath SR, Pal AK, Chhuttani PN, Datta DV |title=The pathology and pathogenesis of fatal hepatic amoebiasis--A study based on 79 autopsy cases |journal=Trans. R. Soc. Trop. Med. Hyg. |volume=73 |issue=2 |pages=188–92 |year=1979 |pmid=473308 |doi= |url=}}</ref> | ||
*Clinical syndromes associated with ''[[Entamoeba histolytica]]'' [[infection]] | *Clinical syndromes associated with ''[[Entamoeba histolytica]]'' [[infection]] | ||
{{familytree/start}} | |||
{{familytree | | | | | | | | | | | A01| | | | | | | | | | | |A01='''Entamoeba histolytica'''}} | |||
{{familytree | | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|.| }} | |||
{{familytree | | | | B01 | | | | | | | | | | | | | B02 |B01='''Intestinal'''|B02='''Extra intestinal'''}} | |||
{{familytree/end}} | |||
===Pathogenesis=== | ===Pathogenesis=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Ameoebic liver abscess is caused by a protozoan Entamoeba histolytica. It is the most common extraintestinal manifestation of amoebiasis.
Pathophysiology
- Amoebic liver abscess is the most common extraintestinal manifestation of amoebiasis.
- There are two genetically different species of entamoeba.[1] They are
- Mode of transmission of Entamoeba histolytica include
- Fecal-oral route (ingestion of food and water contaminated with feces containing cysts)
- Hepatocyte programmed cell death induced by Entamoeba histolytica causes amoebic liver abscess.
- The infection is transmitted to liver by portal venous system.[2]
- Clinical syndromes associated with Entamoeba histolytica infection
| Entamoeba histolytica | |||||||||||||||||||||||||||||||||||||||||||||||
| Intestinal | Extra intestinal | ||||||||||||||||||||||||||||||||||||||||||||||
Pathogenesis
References
- ↑ Gonin P, Trudel L (2003). "Detection and differentiation of Entamoeba histolytica and Entamoeba dispar isolates in clinical samples by PCR and enzyme-linked immunosorbent assay". J Clin Microbiol. 41 (1): 237–41. PMC 149615. PMID 12517854.
- ↑ Aikat BK, Bhusnurmath SR, Pal AK, Chhuttani PN, Datta DV (1979). "The pathology and pathogenesis of fatal hepatic amoebiasis--A study based on 79 autopsy cases". Trans. R. Soc. Trop. Med. Hyg. 73 (2): 188–92. PMID 473308.