Amoebic liver abscess medical therapy

Liver abscess Main Page
Amoebic liver abscess Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating amoebic liver abscess from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Diagnostic Approach
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Ultrasound
Other Imaging Studies
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Amoebic liver abscess medical therapy On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Amoebic liver abscess medical therapy All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Amoebic liver abscess medical therapy
CDC on Amoebic liver abscess medical therapy
Amoebic liver abscess medical therapy in the news
Blogs on Amoebic liver abscess medical therapy
Directions to Hospitals Treating Type chapter name here
Risk calculators and risk factors for Amoebic liver abscess medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Medical Therapy

Pharmocotherapy for E histolytica include:

Site Of Infection	Treatment
Intraluminal infection	Iodoquinol 650mg tid X 20 days Diloxanide furoate 500mg tid X 20 days Paramomycin 30mg/kg/day X 10 days (in 3 divided doses)
Amoebic liver abscess	Metronidazole 800mg tid PO X 10days (500mg qid IV)
Invasive colitis	Metronidazole 800mg tid X 5 days Tinidazole 1 gm bd X 3 days

Current treatment recommendations of E histolytica includes

• With medical therapy alone, the cure rates of more than 90% have been reported, with the resolution of pain, fever, and anorexia with in 72h to 96h.

Treatment phase	Drug	Adult	Pediatric
Initial treatment of amoebic liver abscess	Metronidazole	750 mg PO TID × 7–10 days	35–50 mg/kg/day DIVIDED TID × 7–10 days
	Tinidazole	2 g once PO daily × 3 days	>3 years: 50 mg/kg/day (max 2 g) PO in 1 dose × 3 days
Clearance of luminal cysts	Iodoquinol	650 mg PO TID × 20 days	30–40 mg/kg/day DIVIDED TID × 20 days (max 2 g/day)
	Paromomycin	500 mg PO TID × 7 days OR 25–35 mg/kg/day DIVIDED TID × 7 days	25–35 mg/kg/day DIVIDED TID × 7 days