Cytomegalovirus infection history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

History and Symptoms

CMV Retintis

• Peripheral retinitis can be asymptomatic or present with the following symptoms:
  • Floaters
  • Scotomata
  • Peripheral visual field defects
• Central retinal lesions or lesions impinging on the macula or optic nerve are result in decreased visual acuity and central field defects.

CMV Colitis

Colitis presents with the following symptoms:

• Weight loss
• Anorexia
• Abdominal pain
• Diarrhea
• Fever
• Malaise
• Patients with perforation of the bowel present with acute abdominal pain.

CMV Esophagitis

Patients with cytomegalovirus esophagitis present with symptoms of:

• Odynophagia
• Nausea
• Mid-epigastric or retrosternal discomfort
• Fever

CMV Encephalitis

Patients with cytomegalovirus encephalitis presents with:

• Fever
• Lethargy
• Confusion

CMV Ventriculoencephalitis

• Patients with cytomegalovirus ventricluloencephalitis present:
• Aacute onset of symptoms with focal neurological deficits
• Cranial nerve palsies
• Nystagmus
• Rapid progression to death

CMV Polyradiculomyelopathy

Patients with cytomegalovirus polyradiculomyelopathy present with features similar to Guillian Barre Syndrome and have symptoms such as:

• Bladder incontinence
• Paraplegia with gradual worsening of symptoms over weeks