Toxic shock syndrome screening: Difference between revisions
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==Overview== | ==Overview== | ||
Mainstay of screening for toxic shock syndrome (TSS) is patient education and awareness of the symptoms. Other tests which can be used as a tool to detect the toxic shock syndrome toxin 1 (TSST-1) in patient's blood include the latex agglutination method, and competitive agglutination inhibition assay. | Mainstay of screening for [[toxic shock syndrome]] (TSS) is patient education and awareness of the symptoms. Other tests which can be used as a tool to detect the toxic shock syndrome toxin 1 (TSST-1) in patient's blood include the latex [[agglutination]] method, and competitive [[agglutination]] inhibition assay. | ||
==Screening== | ==Screening== | ||
* Patient education remains a primary key to screening and prevention. Patients should be aware of the symptoms | * Patient education remains a primary key to screening and prevention. Patients should be aware of the symptoms of [[toxic shock syndrome]] and, if symptoms occur, they should seek medical attention immediately. <ref name="pmid1328970">{{cite journal |vauthors=Colbry SL |title=A review of toxic shock syndrome: the need for education still exists |journal=Nurse Pract |volume=17 |issue=9 |pages=39–40, 43, 46 |year=1992 |pmid=1328970 |doi= |url=}}</ref><ref name="pmid11675982">{{cite journal |vauthors=Issa NC, Thompson RL |title=Staphylococcal toxic shock syndrome. Suspicion and prevention are keys to control |journal=Postgrad Med |volume=110 |issue=4 |pages=55–6, 59–62 |year=2001 |pmid=11675982 |doi= |url=}}</ref> | ||
* Latex agglutination method, in which latex particles are sensitized with specific anti-toxic shock syndrome toxin-1 (TSST-1) immunoglobulin, has been found to be a simple and sensitive method for the detection of TSST-1 production by Staphylococcus aureus strains. <ref name="pmid3082921">{{cite journal |vauthors=Igarashi H, Fujikawa H, Shingaki M, Bergdoll MS |title=Latex agglutination test for staphylococcal toxic shock syndrome toxin 1 |journal=J. Clin. Microbiol. |volume=23 |issue=3 |pages=509–12 |year=1986 |pmid=3082921 |pmc=268684 |doi= |url=}}</ref> In order order to exclude other diseases with similar presentation, additional mandatory exclusionary laboratory data needs to be collected. | * Latex agglutination method, in which latex particles are sensitized with specific anti-toxic shock syndrome toxin-1 (TSST-1) [[Antibody|immunoglobulin]], has been found to be a simple and sensitive method for the detection of TSST-1 production by [[Staphylococcus aureus]] strains. <ref name="pmid3082921">{{cite journal |vauthors=Igarashi H, Fujikawa H, Shingaki M, Bergdoll MS |title=Latex agglutination test for staphylococcal toxic shock syndrome toxin 1 |journal=J. Clin. Microbiol. |volume=23 |issue=3 |pages=509–12 |year=1986 |pmid=3082921 |pmc=268684 |doi= |url=}}</ref> In order order to exclude other diseases with similar presentation, additional mandatory exclusionary laboratory data needs to be collected. | ||
* Detection of antibodies to Staphylococcus aureus | * Detection of antibodies to [[Staphylococcus aureus]] toxic Shock Syndrome Toxin-1 using a competitive [[agglutination]] inhibition assay has been found to be a preliminary investigation for medical screening of suspected [[toxic shock syndrome]] and is applicable in situations where [[antibody]] assays are not routinely used for anti-TSST-1 and also where advanced medical equipment is not available.<ref name="pmid12753244">{{cite journal |vauthors=Javid Khojasteh V, Rogan MT, Edwards-Jones V, Foster HA |title=Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay |journal=Lett. Appl. Microbiol. |volume=36 |issue=6 |pages=372–6 |year=2003 |pmid=12753244 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 19:56, 22 May 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Mainstay of screening for toxic shock syndrome (TSS) is patient education and awareness of the symptoms. Other tests which can be used as a tool to detect the toxic shock syndrome toxin 1 (TSST-1) in patient's blood include the latex agglutination method, and competitive agglutination inhibition assay.
Screening
- Patient education remains a primary key to screening and prevention. Patients should be aware of the symptoms of toxic shock syndrome and, if symptoms occur, they should seek medical attention immediately. [1][2]
- Latex agglutination method, in which latex particles are sensitized with specific anti-toxic shock syndrome toxin-1 (TSST-1) immunoglobulin, has been found to be a simple and sensitive method for the detection of TSST-1 production by Staphylococcus aureus strains. [3] In order order to exclude other diseases with similar presentation, additional mandatory exclusionary laboratory data needs to be collected.
- Detection of antibodies to Staphylococcus aureus toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay has been found to be a preliminary investigation for medical screening of suspected toxic shock syndrome and is applicable in situations where antibody assays are not routinely used for anti-TSST-1 and also where advanced medical equipment is not available.[4]
References
- ↑ Colbry SL (1992). "A review of toxic shock syndrome: the need for education still exists". Nurse Pract. 17 (9): 39–40, 43, 46. PMID 1328970.
- ↑ Issa NC, Thompson RL (2001). "Staphylococcal toxic shock syndrome. Suspicion and prevention are keys to control". Postgrad Med. 110 (4): 55–6, 59–62. PMID 11675982.
- ↑ Igarashi H, Fujikawa H, Shingaki M, Bergdoll MS (1986). "Latex agglutination test for staphylococcal toxic shock syndrome toxin 1". J. Clin. Microbiol. 23 (3): 509–12. PMC 268684. PMID 3082921.
- ↑ Javid Khojasteh V, Rogan MT, Edwards-Jones V, Foster HA (2003). "Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay". Lett. Appl. Microbiol. 36 (6): 372–6. PMID 12753244.