Differentiating Fibromyalgia from other diseases: Difference between revisions
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!Differentiating signs and symptoms | !Differentiating signs and symptoms | ||
!Differentiating labs | !Differentiating labs | ||
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|Rheumatoid arthritis | |Rheumatoid arthritis | ||
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* Markers of systemic inflammation (ESR, CRP) are typically elevated. | * Markers of systemic inflammation (ESR, CRP) are typically elevated. | ||
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|SLE | |SLE | ||
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*Positive anti-Smith antibodies | *Positive anti-Smith antibodies | ||
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|[[Chronic fatigue syndrome]] | |[[Chronic fatigue syndrome]] | ||
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*Diagnosis of exclusions | *Diagnosis of exclusions | ||
*Symptoms must present for more than 6 months | *Symptoms must present for more than 6 months | ||
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|Spondyloarthritis | |Spondyloarthritis | ||
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* Bamboo spine on X-ray | * Bamboo spine on X-ray | ||
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|Polymyalgia rheumatica | |Polymyalgia rheumatica | ||
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* An elevated erythrocyte sedimentation rate (ESR) OR C-reactive protein (CRP | * An elevated erythrocyte sedimentation rate (ESR) OR C-reactive protein (CRP | ||
* Response to corticosteroids | * Response to corticosteroids | ||
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|Osteoarthritis | |Osteoarthritis | ||
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* Xray of the involved joints demonstrate degenerative changes | * Xray of the involved joints demonstrate degenerative changes | ||
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|Hypothyroidism | |Hypothyroidism | ||
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*TSH is elevated and free T4 is low. | *TSH is elevated and free T4 is low. | ||
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|Myopathaies(polymyositis and dermatomyositis) | |Myopathaies(polymyositis and dermatomyositis) | ||
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*Muscle biopsy confirms the diagnosis | *Muscle biopsy confirms the diagnosis | ||
*Elevated CPK enzyme | *Elevated CPK enzyme | ||
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|Neuropathy | |Neuropathy |
Revision as of 16:50, 16 June 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Fibromyalgia must be differentiated from other diseases that present with pain, fatigue and sleep disturbance, and symptoms of cognitive dysfunction and psychiatric disease such as rheumatoid arthritis, SLE, chronic fatigue syndrome, spondyloarthritis, polymyalgia rheumatica.[1][2][3][4][5]
Differentiating Fibromyalgia from other Diseases
Fibromyalgia must be differentiated from other diseases that present with pain, fatigue and sleep disturbance, and symptoms of cognitive dysfunction and psychiatric disease such as rheumatoid arthritis, SLE, chronic fatigue syndrome, spondyloarthritis, polymyalgia rheumatica.[1][2][3][4][5]
Disease | Differentiating signs and symptoms | Differentiating labs |
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Rheumatoid arthritis |
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SLE |
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Chronic fatigue syndrome |
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Spondyloarthritis |
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Polymyalgia rheumatica |
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Osteoarthritis |
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Hypothyroidism |
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Myopathaies(polymyositis and dermatomyositis) |
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Neuropathy |
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References
- ↑ 1.0 1.1 Goldenberg DL, Burckhardt C, Crofford L (2004). "Management of fibromyalgia syndrome". JAMA. 292 (19): 2388–95. doi:10.1001/jama.292.19.2388. PMID 15547167.
- ↑ 2.0 2.1 Clauw DJ (2014). "Fibromyalgia: a clinical review". JAMA. 311 (15): 1547–55. doi:10.1001/jama.2014.3266. PMID 24737367.
- ↑ 3.0 3.1 Borchers AT, Gershwin ME (2015). "Fibromyalgia: A Critical and Comprehensive Review". Clin Rev Allergy Immunol. 49 (2): 100–51. doi:10.1007/s12016-015-8509-4. PMID 26445775.
- ↑ 4.0 4.1 Häuser W, Burgmer M, Köllner V, Schaefert R, Eich W, Hausteiner-Wiehle C, Henningsen P (2013). "[Fibromyalgia syndrome as a psychosomatic disorder - diagnosis and therapy according to current evidence-based guidelines]". Z Psychosom Med Psychother (in German). 59 (2): 132–52. doi:10.13109/zptm.2013.59.2.132. PMID 23775553.
- ↑ 5.0 5.1 Eich W, Häuser W, Friedel E, Klement A, Herrmann M, Petzke F, Offenbächer M, Schiltenwolf M, Sommer C, Tölle T, Henningsen P (2008). "[Definition, classification and diagnosis of fibromyalgia syndrome]". Z Rheumatol (in German). 67 (8): 665–6, 668–72, 674–6. doi:10.1007/s00393-008-0404-4. PMID 19050952.