Systemic lupus erythematosus causes: Difference between revisions
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{{CMG}}; {{AE}} {{RT}} | {{CMG}}; {{AE}} {{RT}} | ||
==Overview== | ==Overview== | ||
There are no established causes for systemic lupus erythematosus. Common causes of systemic lupus erythematosus include genetic predisposition, auto-immune disease, and drugs. Less common causes of systemic lupus erythematosus include environmental factors,and exposure to ultraviolet (UV) light. | There are no established causes for systemic lupus erythematosus. Common causes of systemic lupus erythematosus include [[genetic]] predisposition, auto-immune disease, and drugs. Less common causes of systemic lupus erythematosus include environmental factors,and exposure to ultraviolet (UV) light. | ||
==Causes== | ==Causes== | ||
* Genetic predisposition 8749564 | * Genetic predisposition 8749564 | ||
** HLA class polymorphism | ** [[HLA]] class polymorphism | ||
** Complement genes | ** [[Complement]] genes | ||
** Female sexual gene due to high levels of estrogen and prolactin | ** Female sexual gene due to high levels of [[estrogen]] and [[prolactin]] | ||
* Auto-immune disease 7656468 | * [[Auto-immune]] disease 7656468 | ||
* Environmental triggers 12464374 | * Environmental triggers 12464374 | ||
** Infections | ** Infections | ||
*** Epstein-Barr virus (EBV) | *** [[Epstein-Barr virus|Epstein-Barr virus (EBV)]] | ||
*** Trypanosomiasis | *** [[Trypanosomiasis]] | ||
*** Mycobacterial | *** [[Mycobacterial infection|Mycobacterial infections]] | ||
** Exposure to ultraviolet (UV) light | ** Exposure to [[ultraviolet]] (UV) light | ||
*** Can exacerbate or induce systemic manifestations of SLE | *** Can exacerbate or induce systemic manifestations of SLE | ||
* Drug-induced lupus | * Drug-induced lupus | ||
Revision as of 14:47, 30 June 2017
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Systemic lupus erythematosus Microchapters |
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Differentiating Systemic lupus erythematosus from other Diseases |
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Systemic lupus erythematosus causes On the Web |
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Risk calculators and risk factors for Systemic lupus erythematosus causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
There are no established causes for systemic lupus erythematosus. Common causes of systemic lupus erythematosus include genetic predisposition, auto-immune disease, and drugs. Less common causes of systemic lupus erythematosus include environmental factors,and exposure to ultraviolet (UV) light.
Causes
- Genetic predisposition 8749564
- HLA class polymorphism
- Complement genes
- Female sexual gene due to high levels of estrogen and prolactin
- Auto-immune disease 7656468
- Environmental triggers 12464374
- Infections
- Exposure to ultraviolet (UV) light
- Can exacerbate or induce systemic manifestations of SLE
- Drug-induced lupus
- Acebutolol
- Adalimumab
- Anastrozole
- Bupropion
- Captopril
- Cilazapril
- Cinnarizine/thiethylperazine
- Diltiazem
- Docetaxel
- Doxorubicin
- D-penicillamine
- Etanercept
- Gemcitabine
- Glyburide
- Golimumab
- Griseofulvin
- Hydrochlorothiazide
- Infliximab
- Interferon-alpha
- Interferon-beta
- Oxprenolol
- Phenytoin
- Lamotrigine
- Lansoprazole
- Leflunomide
- Leuprorelin
- Naproxen
- Nifedipine
- Nitrendipine
- Omeprazole
- Paclitaxel
- Pantoprazole
- Piroxicam
- Pravastatin
- Ranitidine
- Simvastatin
- Spironolactone
- Tamoxifen
- Terbinafine
- Ticlopidine
- Verapamil
- sulfonamide containing antibiotics, have been associated with SLE exacerbations and should be avoided