Microsporidiosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ogheneochuko Ajari, MB.BS, MS [2];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [3]

History and Symptoms

Microsporidiosis can affect many systems. Intestinal microsporidiosis is the most common form of the disease.

Intestinal microsporidiasis:

In immunocompetent individuals

Intestinal microsporidiasis may be asymptomatic or causes transient diarrhea. In rare cases it might cause chronic diarrhea.

In immunocompromised individuals

• Chronic diarrhea: non bloody watery diarrhea
• Abdominal pain
• Weight loss
• May be associated with nausea and vomiting.

Disseminated disease

Eye involvement

Ocular involvement can cause keratitis which present with red eye, tearing, foreign body sensation

Musculoskeletal involvement

• Muscle pain
• Fever
• Muscle weakness

Central nervous system involvement

• Microsporidiosis may present with symptoms of space occupying lesions such as:
• Headache
• Seizures
• Projectile vomiting