Cretinism natural history, complications and prognosis: Difference between revisions
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===Natural History=== | ===Natural History=== | ||
*The symptoms of | *The symptoms of cretinism usually develop in the first months after birth, and start with symptoms such as jaundice, large fontanelles, and umbilical hernia. | ||
*If left untreated, patients with cretinism may progress to develop mental retardation and neurological manifestations like ataxia and poor motor coordination.<ref name="pmid16444157">{{cite journal| author=Büyükgebiz A| title=Congenital hypothyroidism clinical aspects and late consequences. | journal=Pediatr Endocrinol Rev | year= 2003 | volume= 1 Suppl 2 | issue= | pages= 185-90; discussion 190 | pmid=16444157 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16444157 }}</ref> | |||
*If left untreated, | |||
===Complications=== | ===Complications=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of cretinism usually develop in the first months after birth, and start with symptoms such as jaundice, large fontanelles, and umbilical hernia.
- If left untreated, patients with cretinism may progress to develop mental retardation and neurological manifestations like ataxia and poor motor coordination.[1]
Complications
- Common complications of [disease name] include:
- [complication 1]
- [complication 2]
- [complication 3]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Büyükgebiz A (2003). "Congenital hypothyroidism clinical aspects and late consequences". Pediatr Endocrinol Rev. 1 Suppl 2: 185–90, discussion 190. PMID 16444157.