Cretinism laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
* Measuring the levels of thyroid hormones (T4) and thyroid releasing hormone (TSH) is performed to confirm the diagnosis of cretinism.<ref name="pmid24446653">{{cite journal| author=Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G et al.| title=European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 2 | pages= 363-84 | pmid=24446653 | doi=10.1210/jc.2013-1891 | pmc=4207909 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24446653 }}</ref> | |||
* | * Laboratory findings consistent with cretinism differ according to the underlying cause. Laboratory findings according to the causes are as the following: | ||
** Primary congenital hypothyroidism: High TSH and low T4 levels. | |||
** Subclinical hypothyroidism: High TSH and normal T4 levels. | |||
** Secondary (central) hypothyroidism: Low TSH and low T4 levels. | |||
*Laboratory findings consistent with the | |||
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** | |||
==References== | ==References== | ||
Revision as of 15:04, 28 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal among patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name].
Laboratory Findings
- Measuring the levels of thyroid hormones (T4) and thyroid releasing hormone (TSH) is performed to confirm the diagnosis of cretinism.[1]
- Laboratory findings consistent with cretinism differ according to the underlying cause. Laboratory findings according to the causes are as the following:
- Primary congenital hypothyroidism: High TSH and low T4 levels.
- Subclinical hypothyroidism: High TSH and normal T4 levels.
- Secondary (central) hypothyroidism: Low TSH and low T4 levels.
References
- ↑ Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G; et al. (2014). "European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism". J Clin Endocrinol Metab. 99 (2): 363–84. doi:10.1210/jc.2013-1891. PMC 4207909. PMID 24446653.