Primary biliary cirrhosis history and symptoms: Difference between revisions
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{{Primary biliary cirrhosis}} | {{Primary biliary cirrhosis}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{Anmol}} | ||
==Overview== | ==Overview== | ||
The majority of patients with | The majority of patients with early primary biliary cirrhosis are asymptomatic. | ||
The hallmark of primary biliary cirrhosis is pruritis, worse at night. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. | |||
The hallmark of | |||
==History and Symptoms== | ==History and Symptoms== | ||
*The majority of patients with | *The majority of patients with early primary biliary cirrhosis are asymptomatic.<ref name="pmid12360466">{{cite journal| author=Prince M, Chetwynd A, Newman W, Metcalf JV, James OF| title=Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years. | journal=Gastroenterology | year= 2002 | volume= 123 | issue= 4 | pages= 1044-51 | pmid=12360466 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12360466 }} </ref> | ||
*The hallmark of primary biliary cirrhosis is pruritis, worse at night. The most common symptoms of primary biliary cirrhosis include fatigue, pruritis, and jaundice. | |||
*The hallmark of | *Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. | ||
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. | |||
===History=== | ===History=== | ||
Patients with | Patients with primary biliary cirrhosis may have a positive history of:<ref name="pmid2197212">{{cite journal| author=Witt-Sullivan H, Heathcote J, Cauch K, Blendis L, Ghent C, Katz A et al.| title=The demography of primary biliary cirrhosis in Ontario, Canada. | journal=Hepatology | year= 1990 | volume= 12 | issue= 1 | pages= 98-105 | pmid=2197212 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2197212 }} </ref> | ||
* | *Pruritis, worse at night | ||
* | *Fatigue | ||
* | *Daytime somnolence<ref name="pmid16800007">{{cite journal| author=Newton JL, Gibson GJ, Tomlinson M, Wilton K, Jones D| title=Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence. | journal=Hepatology | year= 2006 | volume= 44 | issue= 1 | pages= 91-8 | pmid=16800007 | doi=10.1002/hep.21230 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16800007 }} </ref> | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of | Common symptoms of primary biliary cirrhosis include:<ref name="pmid2197212">{{cite journal| author=Witt-Sullivan H, Heathcote J, Cauch K, Blendis L, Ghent C, Katz A et al.| title=The demography of primary biliary cirrhosis in Ontario, Canada. | journal=Hepatology | year= 1990 | volume= 12 | issue= 1 | pages= 98-105 | pmid=2197212 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2197212 }} </ref> | ||
* | *Fatigue | ||
* | *Pruritis | ||
* | *Jaundice | ||
*Right upper quadrant pain (10%)<ref name="pmid7942679">{{cite journal| author=Laurin JM, DeSotel CK, Jorgensen RA, Dickson ER, Lindor KD| title=The natural history of abdominal pain associated with primary biliary cirrhosis. | journal=Am J Gastroenterol | year= 1994 | volume= 89 | issue= 10 | pages= 1840-3 | pmid=7942679 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7942679 }} </ref> | |||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of | Less common symptoms of primary biliary cirrhosis include:<ref name="pmid18215315">{{cite journal| author=Kumagi T, Heathcote EJ| title=Primary biliary cirrhosis. | journal=Orphanet J Rare Dis | year= 2008 | volume= 3 | issue= | pages= 1 | pmid=18215315 | doi=10.1186/1750-1172-3-1 | pmc=2266722 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18215315 }} </ref> | ||
* | *Variceal bleeding | ||
* | *Abdominal distension | ||
* | *Hepatic encephalopathy | ||
==References== | ==References== |
Revision as of 16:27, 5 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
The majority of patients with early primary biliary cirrhosis are asymptomatic. The hallmark of primary biliary cirrhosis is pruritis, worse at night. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- The majority of patients with early primary biliary cirrhosis are asymptomatic.[1]
- The hallmark of primary biliary cirrhosis is pruritis, worse at night. The most common symptoms of primary biliary cirrhosis include fatigue, pruritis, and jaundice.
- Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History
Patients with primary biliary cirrhosis may have a positive history of:[2]
- Pruritis, worse at night
- Fatigue
- Daytime somnolence[3]
Common Symptoms
Common symptoms of primary biliary cirrhosis include:[2]
- Fatigue
- Pruritis
- Jaundice
- Right upper quadrant pain (10%)[4]
Less Common Symptoms
Less common symptoms of primary biliary cirrhosis include:[5]
- Variceal bleeding
- Abdominal distension
- Hepatic encephalopathy
References
- ↑ Prince M, Chetwynd A, Newman W, Metcalf JV, James OF (2002). "Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years". Gastroenterology. 123 (4): 1044–51. PMID 12360466.
- ↑ 2.0 2.1 Witt-Sullivan H, Heathcote J, Cauch K, Blendis L, Ghent C, Katz A; et al. (1990). "The demography of primary biliary cirrhosis in Ontario, Canada". Hepatology. 12 (1): 98–105. PMID 2197212.
- ↑ Newton JL, Gibson GJ, Tomlinson M, Wilton K, Jones D (2006). "Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence". Hepatology. 44 (1): 91–8. doi:10.1002/hep.21230. PMID 16800007.
- ↑ Laurin JM, DeSotel CK, Jorgensen RA, Dickson ER, Lindor KD (1994). "The natural history of abdominal pain associated with primary biliary cirrhosis". Am J Gastroenterol. 89 (10): 1840–3. PMID 7942679.
- ↑ Kumagi T, Heathcote EJ (2008). "Primary biliary cirrhosis". Orphanet J Rare Dis. 3: 1. doi:10.1186/1750-1172-3-1. PMC 2266722. PMID 18215315.