Growth hormone deficiency MRI

Growth hormone deficiency Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: {MAD}}

Overview

• There are no MRI findings associated with [disease name].

OR

• [Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

• There are no MRI findings associated with [disease name]. However, an MRI may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].

MRI

• [Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include:
• MRI is highly sensitive to visualize the hypothalamo-hypophyseal tract. After the clinical and biochemical diagnosis of GHD is made [32].

• On T1-weighted imaging, a clear demarcation can be made between the adenohypophysis (after two months of age) and the neurohypophysis, which appears as hyperintense [73]

• This imaging is important to exclude the possibility of a pituitary tumor; it also permits diagnostic characterization by showing the presence or absence of morphological abnormalities such as anterior pituitary hypoplasia, pituitary stalk agenesis, and posterior pituitary ectopia.

• MRI may also provide evidence of severe GHD

• The diagnosis of pituitary stalk interruption syndrome (PSIS) is made [74].

Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID: 16814

Case courtesy of Dr Hani Salam, Radiopaedia.org, rID: 8518