Hypoaldosteronism pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis | Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis can be due to : | ||
* Adrenal Insufficiency: Primary or secondary | * Adrenal Insufficiency: Primary or secondary | ||
* Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase | * Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase |
Revision as of 18:42, 14 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Pathophysiology
Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis can be due to :
- Adrenal Insufficiency: Primary or secondary
- Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase
- Renal disorders: Chronic renal failure and diabetic nephropathy
- Drugs inhibiting aldosterone effect: NSAID, spironolactone, and triamterene