Hypoaldosteronism pathophysiology: Difference between revisions

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==Pathophysiology==
==Pathophysiology==
Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis which can be due to :
Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis can be due to :
* Adrenal Insufficiency: Primary or secondary
* Adrenal Insufficiency: Primary or secondary
* Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase
* Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase

Revision as of 18:42, 14 August 2017

Hypoaldosteronism Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Pathophysiology

Hypoaldosteronism is defined as decreased levels of the hormone aldosterone (Normal range: 1-21 ng/dL). Hypoaldosteronism from decreased aldosterone synthesis can be due to :

  • Adrenal Insufficiency: Primary or secondary
  • Enzyme deficiency: Aldosterone synthase, 21 hydroxylase, and 11B hydroxylase
  • Renal disorders: Chronic renal failure and diabetic nephropathy
  • Drugs inhibiting aldosterone effect: NSAID, spironolactone, and triamterene

References

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