Hypoaldosteronism classification: Difference between revisions
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==Overview== | ==Overview== | ||
Hypoaldosteronism may be classified into two categories depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance. | Hypoaldosteronism may be classified into two categories depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance. | ||
==Classification== | ==Classification== | ||
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==Based on the level of plasma renin== | ==Based on the level of plasma renin== | ||
Renin deficiency is the most common cause of hypoaldosteronism. Juxtaglomerular apparatus in the kidneys produce the hormone renin in response to decreased plasma sodium concentration or decreased renal perfusion pressure. Any condition that affects the kidney may lead to decreased levels of the hormone renin. Conditions affecting the adrenal cortex leads to increased levels of renin and decreased levels of aldosterone. | |||
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{{familytree | | | | | | | | A01 |A01=Hypoaldosteronism}} | {{familytree | | | | | | | | A01 |A01=Hypoaldosteronism}} | ||
Revision as of 15:45, 25 August 2017
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Hypoaldosteronism Microchapters |
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Hypoaldosteronism classification On the Web |
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American Roentgen Ray Society Images of Hypoaldosteronism classification |
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Risk calculators and risk factors for Hypoaldosteronism classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hypoaldosteronism may be classified into two categories depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance.
Classification
Hypoaldosteronism may be classified into two categories depending on the level of plasma renin and depending on the level of aldosterone into hyporeninemic hypoaldosteronism or hyperreninemic hypoaldosteronism, and aldosterone deficiency or aldosterone resistance.
Based on the level of plasma renin
Renin deficiency is the most common cause of hypoaldosteronism. Juxtaglomerular apparatus in the kidneys produce the hormone renin in response to decreased plasma sodium concentration or decreased renal perfusion pressure. Any condition that affects the kidney may lead to decreased levels of the hormone renin. Conditions affecting the adrenal cortex leads to increased levels of renin and decreased levels of aldosterone.
| Hypoaldosteronism | |||||||||||||||||||||||||||||||||||||||
| Hyporeninemic Hypoaldosteronism | Hyperreninemic Hypoaldosteronism | ||||||||||||||||||||||||||||||||||||||
| •Renal insufficiency •Diabetic nephropathy •Sickle cell disease | •Addison's disease • Any severe illness such as malignancy or sepsis | ||||||||||||||||||||||||||||||||||||||
Based on the level of aldosterone
| Hypoaldosteronism | |||||||||||||||||||||||||||||||||||||||
| Aldosterone deficiency | Aldosterone resistance | ||||||||||||||||||||||||||||||||||||||
| •Renal insufficiency •Adrenal insufficiency • Diabetic nephropathy •Sickle cell disease •Critical illness •Congenital isolated hypoaldosteronism • Drugs such as ACEi, ARBs and Heparin | • Pseudohypoaldosteronism type 1 • Aldosterone antagonists • Epithelial sodium channel blockers • Calcineurin inhibitors | ||||||||||||||||||||||||||||||||||||||