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| ==Medical Therapy== | | ==Medical Therapy== |
| *Pharmacologic medical therapy is recommended among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3]. | | *Pharmacologic medical therapy is recommended among patients with Goiter. |
| *Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3]. | | *In cases of hypothyroidism, thyroid hormone replacement with levothyroxine may help resolve hypothyroidism symptoms and also help with the slow release of TSH (Thyroid Stimulating Hormone) from pituitary which would result in the decrease in the size of the goiter. |
| *Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].
| | *In hyperthyroidism, treatment targeted at normalizing hormone levels is considered. |
| *Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].
| | *In cases of inflammation of thyroid gland, medication to treat the inflammation are generally prescribed. For goiters associated with hyperthyroidism, you may need medications to normalize hormone levels. |
| ===Disease Name===
| | *In some cases, radioactive iodine may be used to treat an overactive thyroid gland. Radioactive iodine is prescribed as an oral medication which helps destroy thyroid cells resulting in the decreasing the size of the goiter. This therapy may also lead to under-activity of the thyroid gland. |
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| * '''1 Stage 1 - Name of stage'''
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| ** 1.1 '''Specific Organ system involved 1'''
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| *** 1.1.1 '''Adult'''
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| **** Preferred regimen (1): [[drug name]] 100 mg PO q12h for 10-21 days '''(Contraindications/specific instructions)'''
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| **** Preferred regimen (2): [[drug name]] 500 mg PO q8h for 14-21 days
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| **** Preferred regimen (3): [[drug name]] 500 mg q12h for 14-21 days
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| **** Alternative regimen (1): [[drug name]] 500 mg PO q6h for 7–10 days
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| **** Alternative regimen (2): [[drug name]] 500 mg PO q12h for 14–21 days
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| **** Alternative regimen (3): [[drug name]] 500 mg PO q6h for 14–21 days
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| *** 1.1.2 '''Pediatric'''
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| **** 1.1.2.1 (Specific population e.g. '''children < 8 years of age''')
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| ***** Preferred regimen (1): [[drug name]] 50 mg/kg PO per day q8h (maximum, 500 mg per dose)
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| ***** Preferred regimen (2): [[drug name]] 30 mg/kg PO per day in 2 divided doses (maximum, 500 mg per dose)
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| ***** Alternative regimen (1): [[drug name]]10 mg/kg PO q6h (maximum, 500 mg per day)
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| ***** Alternative regimen (2): [[drug name]] 7.5 mg/kg PO q12h (maximum, 500 mg per dose) | |
| ***** Alternative regimen (3): [[drug name]] 12.5 mg/kg PO q6h (maximum, 500 mg per dose)
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| ****1.1.2.2 (Specific population e.g. ''''''children < 8 years of age'''''') | |
| ***** Preferred regimen (1): [[drug name]] 4 mg/kg/day PO q12h（maximum, 100 mg per dose）
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| ***** Alternative regimen (1): [[drug name]] 10 mg/kg PO q6h (maximum, 500 mg per day)
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| ***** Alternative regimen (2): [[drug name]] 7.5 mg/kg PO q12h (maximum, 500 mg per dose)
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| ***** Alternative regimen (3): [[drug name]] 12.5 mg/kg PO q6h (maximum, 500 mg per dose) | |
| ** 2.1 '''Specific Organ system involved 2'''
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| *** 2.1.1 '''Adult'''
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| **** Preferred regimen (1): [[drug name]] 500 mg PO q8h
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| *** 2.1.2 '''Pediatric'''
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| **** Preferred regimen (1): [[drug name]] 50 mg/kg/day PO q8h (maximum, 500 mg per dose)
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| * 2 '''Stage 2 - Name of stage'''
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| ** 2.1 '''Specific Organ system involved 1 '''
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| **: '''Note (1):'''
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| **: '''Note (2)''':
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| **: '''Note (3):'''
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| *** 2.1.1 '''Adult'''
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| **** Parenteral regimen
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| ***** Preferred regimen (1): [[drug name]] 2 g IV q24h for 14 (14–21) days
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| ***** Alternative regimen (1): [[drug name]] 2 g IV q8h for 14 (14–21) days
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| ***** Alternative regimen (2): [[drug name]] 18–24 MU/day IV q4h for 14 (14–21) days
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| **** Oral regimen
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| ***** Preferred regimen (1): [[drug name]] 500 mg PO q8h for 14 (14–21) days
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| ***** Preferred regimen (2): [[drug name]] 100 mg PO q12h for 14 (14–21) days
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| ***** Preferred regimen (3): [[drug name]] 500 mg PO q12h for 14 (14–21) days
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| ***** Alternative regimen (1): [[drug name]] 500 mg PO q6h for 7–10 days
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| ***** Alternative regimen (2): [[drug name]] 500 mg PO q12h for 14–21 days
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| ***** Alternative regimen (3):[[drug name]] 500 mg PO q6h for 14–21 days
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| *** 2.1.2 '''Pediatric'''
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| **** Parenteral regimen
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| ***** Preferred regimen (1): [[drug name]] 50–75 mg/kg IV q24h for 14 (14–21) days (maximum, 2 g)
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| ***** Alternative regimen (1): [[drug name]] 150–200 mg/kg/day IV q6–8h for 14 (14–21) days (maximum, 6 g per day)
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| ***** Alternative regimen (2): [[drug name]] 200,000–400,000 U/kg/day IV q4h for 14 (14–21) days (maximum, 18–24 million U per day) ''''''(Contraindications/specific instructions)''''''
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| **** Oral regimen
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| ***** Preferred regimen (1): [[drug name]] 50 mg/kg/day PO q8h for 14 (14–21) days (maximum, 500 mg per dose)
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| ***** Preferred regimen (2): [[drug name]] '''(for children aged ≥ 8 years)''' 4 mg/kg/day PO q12h for 14 (14–21) days (maximum, 100 mg per dose)
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| ***** Preferred regimen (3): [[drug name]] 30 mg/kg/day PO q12h for 14 (14–21) days (maximum, 500 mg per dose)
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| ***** Alternative regimen (1): [[drug name]] 10 mg/kg PO q6h 7–10 days (maximum, 500 mg per day)
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| ***** Alternative regimen (2): [[drug name]] 7.5 mg/kg PO q12h for 14–21 days (maximum, 500 mg per dose)
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| ***** Alternative regimen (3): [[drug name]] 12.5 mg/kg PO q6h for 14–21 days (maximum,500 mg per dose)
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| ** 2.2 '<nowiki/>'''''Other Organ system involved 2''''''
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| **: '''Note (1):'''
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| **: '''Note (2)''':
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| **: '''Note (3):'''
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| *** 2.2.1 '''Adult'''
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| **** Parenteral regimen
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| ***** Preferred regimen (1): [[drug name]] 2 g IV q24h for 14 (14–21) days
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| ***** Alternative regimen (1): [[drug name]] 2 g IV q8h for 14 (14–21) days
| |
| ***** Alternative regimen (2): [[drug name]] 18–24 MU/day IV q4h for 14 (14–21) days
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| **** Oral regimen
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| ***** Preferred regimen (1): [[drug name]] 500 mg PO q8h for 14 (14–21) days
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| ***** Preferred regimen (2): [[drug name]] 100 mg PO q12h for 14 (14–21) days
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| ***** Preferred regimen (3): [[drug name]] 500 mg PO q12h for 14 (14–21) days
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| ***** Alternative regimen (1): [[drug name]] 500 mg PO q6h for 7–10 days
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| ***** Alternative regimen (2): [[drug name]] 500 mg PO q12h for 14–21 days
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| ***** Alternative regimen (3):[[drug name]] 500 mg PO q6h for 14–21 days
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| *** 2.2.2 '''Pediatric'''
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| **** Parenteral regimen
| |
| ***** Preferred regimen (1): [[drug name]] 50–75 mg/kg IV q24h for 14 (14–21) days (maximum, 2 g)
| |
| ***** Alternative regimen (1): [[drug name]] 150–200 mg/kg/day IV q6–8h for 14 (14–21) days (maximum, 6 g per day)
| |
| ***** Alternative regimen (2): [[drug name]] 200,000–400,000 U/kg/day IV q4h for 14 (14–21) days (maximum, 18–24 million U per day)
| |
| **** Oral regimen
| |
| ***** Preferred regimen (1): [[drug name]] 50 mg/kg/day PO q8h for 14 (14–21) days (maximum, 500 mg per dose)
| |
| ***** Preferred regimen (2): [[drug name]] 4 mg/kg/day PO q12h for 14 (14–21) days (maximum, 100 mg per dose)
| |
| ***** Preferred regimen (3): [[drug name]] 30 mg/kg/day PO q12h for 14 (14–21) days (maximum, 500 mg per dose)
| |
| ***** Alternative regimen (1): [[drug name]] 10 mg/kg PO q6h 7–10 days (maximum, 500 mg per day)
| |
| ***** Alternative regimen (2): [[drug name]] 7.5 mg/kg PO q12h for 14–21 days (maximum, 500 mg per dose)
| |
| ***** Alternative regimen (3): [[drug name]] 12.5 mg/kg PO q6h for 14–21 days (maximum,500 mg per dose)
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| ==References== | | ==References== |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There is no treatment for [disease name]; the mainstay of therapy is supportive care.
OR
Supportive therapy for [disease name] includes [therapy 1], [therapy 2], and [therapy 3].
OR
The majority of cases of [disease name] are self-limited and require only supportive care.
OR
[Disease name] is a medical emergency and requires prompt treatment.
OR
The mainstay of treatment for [disease name] is [therapy].
OR
The optimal therapy for [malignancy name] depends on the stage at diagnosis.
OR
[Therapy] is recommended among all patients who develop [disease name].
OR
Pharmacologic medical therapy is recommended among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3].
OR
Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].
OR
Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].
OR
Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].
Medical Therapy
- Pharmacologic medical therapy is recommended among patients with Goiter.
- In cases of hypothyroidism, thyroid hormone replacement with levothyroxine may help resolve hypothyroidism symptoms and also help with the slow release of TSH (Thyroid Stimulating Hormone) from pituitary which would result in the decrease in the size of the goiter.
- In hyperthyroidism, treatment targeted at normalizing hormone levels is considered.
- In cases of inflammation of thyroid gland, medication to treat the inflammation are generally prescribed. For goiters associated with hyperthyroidism, you may need medications to normalize hormone levels.
- In some cases, radioactive iodine may be used to treat an overactive thyroid gland. Radioactive iodine is prescribed as an oral medication which helps destroy thyroid cells resulting in the decreasing the size of the goiter. This therapy may also lead to under-activity of the thyroid gland.
References
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