Fournier gangrene epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The overall [[incidence]] of Fournier gangrene annually is 1.6 cases per 100,000 males. The [[incidence]] peaked and remained steady after age 50 at 3.3 cases per 100,000 males. Fournier gangrene affects individuals of all ages but more commonly affects individuals older than 50 years of age.<ref name="pmid23251819">{{cite journal| author=Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS| title=Fournier's Gangrene: Current Practices. | journal=ISRN Surg | year= 2012 | volume= 2012 | issue= | pages= 942437 | pmid=23251819 | doi=10.5402/2012/942437 | pmc=3518952 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23251819 }} </ref><ref name="pmid23578806">{{cite journal| author=Shyam DC, Rapsang AG| title=Fournier's gangrene. | journal=Surgeon | year= 2013 | volume= 11 | issue= 4 | pages= 222-32 | pmid=23578806 | doi=10.1016/j.surge.2013.02.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23578806 }} </ref>. Men are more commonly affected with Fournier gangrene than women, with a male:female ratio of 10:1.<ref name="pmid26445600">{{cite journal| author=Chennamsetty A, Khourdaji I, Burks F, Killinger KA| title=Contemporary diagnosis and management of Fournier's gangrene. | journal=Ther Adv Urol | year= 2015 | volume= 7 | issue= 4 | pages= 203-15 | pmid=26445600 | doi=10.1177/1756287215584740 | pmc=4580094 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26445600 }} </ref><ref name="pmid23578806">{{cite journal| author=Shyam DC, Rapsang AG| title=Fournier's gangrene. | journal=Surgeon | year= 2013 | volume= 11 | issue= 4 | pages= 222-32 | pmid=23578806 | doi=10.1016/j.surge.2013.02.001 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23578806 }} </ref>. Mortality rate decreases with early aggressive treatment. The mortality rate of Fournier gangrene is between 20% to 80%. Higher mortality rates are found in [[diabetes|daibetics]], alcoholics and those with colorectal sources of [[infection]].<ref name="pmid20062653">{{cite journal| author=Moslemi MK, Sadighi Gilani MA, Moslemi AA, Arabshahi A| title=Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report. | journal=Cases J | year= 2009 | volume= 2 | issue= | pages= 9136 | pmid=20062653 | doi=10.1186/1757-1626-2-9136 | pmc=2803933 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20062653 }} </ref> | |||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
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Steven C. Campbell, M.D., Ph.D.; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[1]; Jesus Rosario Hernandez, M.D. [2]
Overview
The overall incidence of Fournier gangrene annually is 1.6 cases per 100,000 males. The incidence peaked and remained steady after age 50 at 3.3 cases per 100,000 males. Fournier gangrene affects individuals of all ages but more commonly affects individuals older than 50 years of age.[1][2]. Men are more commonly affected with Fournier gangrene than women, with a male:female ratio of 10:1.[3][2]. Mortality rate decreases with early aggressive treatment. The mortality rate of Fournier gangrene is between 20% to 80%. Higher mortality rates are found in daibetics, alcoholics and those with colorectal sources of infection.[4]
Epidemiology and Demographics
Incidence
Incidence of Fournier gangrene in the United states:[5]
- The overall incidence of Fournier gangrene annually is 1.6 cases per 100,000 males. The incidence peaked and remained steady after age 50 at 3.3 cases per 100,000 males.
- The incidence of Fournier gangrene increased 0.2 per 100,000 males for each 1% increase in the regional prevalence of diabetes.
- The incidence rate was highest in the southern U.S. and lowest in the western and mid-western U.S.
-
![Distribution of annual cases per hospital.[5]](/images/4/45/Epidemiology.jpg)
Distribution of annual cases per hospital.[5]
![Distribution of annual cases per hospital.[5]](/index.php/File:Epidemiology.jpg)
Age
Fournier gangrene affects individuals of all ages but more commonly affects individuals older than 50 years of age.[1][2]
Gender
Men are more commonly affected with Fournier gangrene than women, with a male:female ratio of 10:1.[3][2]
Mortality
- Mortality rate decreases with early aggressive treatment.
- The mortality rate of Fournier gangrene is between 20% to 80%. Higher mortality rates are found in daibetics, alcoholics and those with colorectal sources of infection.[4]
References
- ↑ 1.0 1.1 Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS (2012). "Fournier's Gangrene: Current Practices". ISRN Surg. 2012: 942437. doi:10.5402/2012/942437. PMC 3518952. PMID 23251819.
- ↑ 2.0 2.1 2.2 2.3 Shyam DC, Rapsang AG (2013). "Fournier's gangrene". Surgeon. 11 (4): 222–32. doi:10.1016/j.surge.2013.02.001. PMID 23578806.
- ↑ 3.0 3.1 Chennamsetty A, Khourdaji I, Burks F, Killinger KA (2015). "Contemporary diagnosis and management of Fournier's gangrene". Ther Adv Urol. 7 (4): 203–15. doi:10.1177/1756287215584740. PMC 4580094. PMID 26445600.
- ↑ 4.0 4.1 Moslemi MK, Sadighi Gilani MA, Moslemi AA, Arabshahi A (2009). "Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report". Cases J. 2: 9136. doi:10.1186/1757-1626-2-9136. PMC 2803933. PMID 20062653.
- ↑ 5.0 5.1 Sorensen MD, Krieger JN (2016). "Fournier's Gangrene: Epidemiology and Outcomes in the General US Population". Urol Int. 97 (3): 249–259. doi:10.1159/000445695. PMID 27172977.