Fournier gangrene laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
The most important laboratory findings in necrotizing fasciitis include [[C reactive protein|C-reactive protein]], total [[white blood cell|white blood cell]] count, [[Hemoglobin]], [[Sodium]], [[Creatinine]], [[Glucose]]. The main importance of these laboratory findings are due to their usage as a distinguishing method for differentiating [[necrotizing fasciitis]] from other soft tissue infections. | |||
'''Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system''' | '''Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system''' | ||
LRINEC is a diagnostic scoring system used to distinguish [[necrotizing fasciitis]] from other soft tissue infections.<ref name="pmid15241098">{{cite journal| author=Wong CH, Khin LW, Heng KS, Tan KC, Low CO| title=The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. | journal=Crit Care Med | year= 2004 | volume= 32 | issue= 7 | pages= 1535-41 | pmid=15241098 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15241098 }} </ref><ref name="pmid23251819">{{cite journal| author=Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS| title=Fournier's Gangrene: Current Practices. | journal=ISRN Surg | year= 2012 | volume= 2012 | issue= | pages= 942437 | pmid=23251819 | doi=10.5402/2012/942437 | pmc=3518952 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23251819 }} </ref> It was first established by Wong et al in 2004. | LRINEC is a diagnostic scoring system used to distinguish [[necrotizing fasciitis]] from other soft tissue infections.<ref name="pmid15241098">{{cite journal| author=Wong CH, Khin LW, Heng KS, Tan KC, Low CO| title=The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. | journal=Crit Care Med | year= 2004 | volume= 32 | issue= 7 | pages= 1535-41 | pmid=15241098 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15241098 }} </ref><ref name="pmid23251819">{{cite journal| author=Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS| title=Fournier's Gangrene: Current Practices. | journal=ISRN Surg | year= 2012 | volume= 2012 | issue= | pages= 942437 | pmid=23251819 | doi=10.5402/2012/942437 | pmc=3518952 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23251819 }} </ref> It was first established by Wong et al in 2004. | ||
{| class="wikitable" style="border: 2; background: none;" | {| class="wikitable" style="border: 2; background: none;" | ||
! colspan="1" rowspan="2" style="border: 1; background: 1;"| Variable | ! colspan="1" rowspan="2" style="border: 1; background: 1;" | Variable | ||
! colspan="5" rowspan="1"| Score | ! colspan="5" rowspan="1" | Score | ||
|- | |- style="border: 1; background: 1;" colspan="1" rowspan="2" | ||
! 0 || +1 || +2 || +3 || +4 | ! 0 || +1 || +2 || +3 || +4 | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| [[C reactive protein|C-reactive protein]] (mg/dL) | ! rowspan="1" style="border: 1; background: none;" | [[C reactive protein|C-reactive protein]] (mg/dL) | ||
| <150 || || || || >150 | | <150 || || || || >150 | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| Total [[white blood cell|White Blood Cell]] Count (/mm3) | ! rowspan="1" style="border: 1; background: none;" | Total [[white blood cell|White Blood Cell]] Count (/mm3) | ||
| <15 || 15-25 || >25 || || | | <15 || 15-25 || >25 || || | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| [[Hemoglobin]] (g/dL) | ! rowspan="1" style="border: 1; background: none;" | [[Hemoglobin]] (g/dL) | ||
| <13.5 || 11-13.5 || <11 || || | | <13.5 || 11-13.5 || <11 || || | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| [[Sodium]] (mmol/L) | ! rowspan="1" style="border: 1; background: none;" | [[Sodium]] (mmol/L) | ||
| ≥135 || || <135 || || | | ≥135 || || <135 || || | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| [[Creatinine]] (μmol/L) | ! rowspan="1" style="border: 1; background: none;" | [[Creatinine]] (μmol/L) | ||
| <141 || || >141 || || | | <141 || || >141 || || | ||
|- | |- | ||
! rowspan="1" style="border: 1; background: none;"| [[Glucose]] (mmol/L) | ! rowspan="1" style="border: 1; background: none;" | [[Glucose]] (mmol/L) | ||
| <10 || >10 || || || | | <10 || >10 || || || | ||
|} | |} | ||
Revision as of 21:12, 6 September 2017
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Steven C. Campbell, M.D., Ph.D.; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[1]; Jesus Rosario Hernandez, M.D. [2]
Overview
The most important laboratory findings in necrotizing fasciitis include C-reactive protein, total white blood cell count, Hemoglobin, Sodium, Creatinine, Glucose. The main importance of these laboratory findings are due to their usage as a distinguishing method for differentiating necrotizing fasciitis from other soft tissue infections.
Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system
LRINEC is a diagnostic scoring system used to distinguish necrotizing fasciitis from other soft tissue infections.[1][2] It was first established by Wong et al in 2004.
| Variable | Score | ||||
|---|---|---|---|---|---|
| 0 | +1 | +2 | +3 | +4 | |
| C-reactive protein (mg/dL) | <150 | >150 | |||
| Total White Blood Cell Count (/mm3) | <15 | 15-25 | >25 | ||
| Hemoglobin (g/dL) | <13.5 | 11-13.5 | <11 | ||
| Sodium (mmol/L) | ≥135 | <135 | |||
| Creatinine (μmol/L) | <141 | >141 | |||
| Glucose (mmol/L) | <10 | >10 | |||
- Score of ≤5 indicates low risk
- Score of 6-7 indicates intermediate risk
- Score of ≥8 indicates high risk
References
- ↑ Wong CH, Khin LW, Heng KS, Tan KC, Low CO (2004). "The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections". Crit Care Med. 32 (7): 1535–41. PMID 15241098.
- ↑ Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS (2012). "Fournier's Gangrene: Current Practices". ISRN Surg. 2012: 942437. doi:10.5402/2012/942437. PMC 3518952. PMID 23251819.