Insulinoma surgery: Difference between revisions
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===Malignant Tumors=== | ===Malignant Tumors=== | ||
*Resectable tumors:<ref name="pmid23430217">{{cite journal| author=Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y et al.| title=Diagnosis and management of insulinoma. | journal=World J Gastroenterol | year= 2013 | volume= 19 | issue= 6 | pages= 829-37 | pmid=23430217 | doi=10.3748/wjg.v19.i6.829 | pmc=PMC3574879 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23430217 }} </ref><ref name=surgery> Inulinoma. national library of medicine. https://www.nlm.nih.gov/medlineplus/ency/article/000387.htm</ref><ref name="pmid1677058">{{cite journal| author=Service FJ, McMahon MM, O'Brien PC, Ballard DJ| title=Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study. | journal=Mayo Clin Proc | year= 1991 | volume= 66 | issue= 7 | pages= 711-9 | pmid=1677058 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1677058 }} </ref> | *Resectable tumors:<ref name="pmid23430217">{{cite journal| author=Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y et al.| title=Diagnosis and management of insulinoma. | journal=World J Gastroenterol | year= 2013 | volume= 19 | issue= 6 | pages= 829-37 | pmid=23430217 | doi=10.3748/wjg.v19.i6.829 | pmc=PMC3574879 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23430217 }} </ref><ref name=surgery> Inulinoma. national library of medicine. https://www.nlm.nih.gov/medlineplus/ency/article/000387.htm</ref><ref name="pmid1677058">{{cite journal| author=Service FJ, McMahon MM, O'Brien PC, Ballard DJ| title=Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study. | journal=Mayo Clin Proc | year= 1991 | volume= 66 | issue= 7 | pages= 711-9 | pmid=1677058 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1677058 }} </ref> | ||
:*Aggressive surgical resection, including extended pancreatic resection, [[liver resection]], and/or [[liver transplantation]] | :*Aggressive surgical resection, including extended pancreatic resection with lymph nodes, [[liver resection]], and/or [[liver transplantation]] | ||
:*Post-surgical chemoembolization or radiofrequency ablation of tumors to control hypoglycemia | :*Post-surgical chemoembolization or radiofrequency ablation of tumors to control hypoglycemia | ||
Revision as of 16:14, 7 September 2017
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Insulinoma Microchapters |
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Insulinoma surgery On the Web |
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American Roentgen Ray Society Images of Insulinoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]Parminder Dhingra, M.D. [3]
Overview
Surgery is the mainstay of treatment for insulinoma. The feasibility of surgery depends on the stage of insulinoma at diagnosis.[1][2]
Surgery
Surgery is the mainstay of treatment for benign and resectable malignant insulinoma. The feasibility of surgery depends on the stage of insulinoma at diagnosis.
Benign Tumors
- Surgical resection is treatment of choice (minimal invasive surgery)
- Enucleation
- Partial pancreatectomy
- Middle pancreatectomy
- Multiple, unencapsulated, >4 cm in diameter, and involves or is near the main pancreatic duct:
- Radical resection
Malignant Tumors
- Aggressive surgical resection, including extended pancreatic resection with lymph nodes, liver resection, and/or liver transplantation
- Post-surgical chemoembolization or radiofrequency ablation of tumors to control hypoglycemia
- Unresectable tumors
- Octreotide administration
- Continous glucose monitoring
- Radiofrequecy ablation
- Embolization
- Intra-arterial chemotherapy
Indications
- Repeated and prolonged symptoms of hypoglycemia
References
- ↑ 1.0 1.1 1.2 Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y; et al. (2013). "Diagnosis and management of insulinoma". World J Gastroenterol. 19 (6): 829–37. doi:10.3748/wjg.v19.i6.829. PMC 3574879. PMID 23430217.
- ↑ 2.0 2.1 2.2 Inulinoma. national library of medicine. https://www.nlm.nih.gov/medlineplus/ency/article/000387.htm
- ↑ 3.0 3.1 Service FJ, McMahon MM, O'Brien PC, Ballard DJ (1991). "Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study". Mayo Clin Proc. 66 (7): 711–9. PMID 1677058.