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**'''Tumor-like  lesions'''
**'''Tumor-like  lesions'''


*Goiter may be also be classified according to various classification methods based on the following:
*'''<u>Goiter may be also be classified according to various classification methods based on the following</u>''':
**Etiological classification
**''Etiological classification''
**Epidemiological classification
**''Epidemiological classification''
**Anatomical classification
**''Anatomical classification''
**Pathological classification
**''Pathological classification''
**Functional classification
**''Functional classification''
**Morphological classification
**''Morphological classification''


*Etiological classification:
*'''<u>Etiological classification:</u>'''
**Physiological goitre: Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty
**Physiological goitre: Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty
**Pathological goitre: Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions
**Pathological goitre: Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions


*Epidemiological classification:
*'''<u>Epidemiological classification:</u>'''
**Familial goitres: Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis  
**Familial goitres: Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis  
**Endemic goitres: Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality
**Endemic goitres: Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality
**Sporadic goitres: Goitres that run sporadically
**Sporadic goitres: Goitres that run sporadically


*Anatomical classification:
*'''<u>Anatomical classification:</u>'''
**Cervical goitre: Goitre situated on the anterior aspect of the neck
**Cervical goitre: Goitre situated on the anterior aspect of the neck
**Retrosternal goitre: Goitre extends downward and get situated behind the sternum
**Retrosternal goitre: Goitre extends downward and get situated behind the sternum
**Intrathoracic goitre: The type of goitre which extends into thoracic cavity
**Intrathoracic goitre: The type of goitre which extends into thoracic cavity


*Pathological classification:
*'''<u>Pathological classification:</u>'''
**Simple goitres
**Simple goitres
**Toxic goitres  
**Toxic goitres  
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**Miscellaneous (Other rare types)
**Miscellaneous (Other rare types)


*Functional classification:
*'''<u>Functional classification:</u>'''
**Toxic goitre: Type of goitre associated with thyroid hyperfunction (hyperthyroidism)
**Toxic goitre: Type of goitre associated with thyroid hyperfunction (hyperthyroidism)
**Non-toxic: Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid)
**Non-toxic: Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid)


*Morphological classification: According to the texture of the gland
*'''<u>Morphological classification:</u>''' According to the texture of the gland
**Diffuse goitre
**Diffuse goitre
**Nodular goitre
**Nodular goitre

Revision as of 02:53, 11 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • In 1974, an international committee of thyroid pathologists published the first WHO histological classification of thyroid tumours which had served as a basis for various clinical, pathological, and epidemiological studies
  • Goiter may also be classified according to various classification methods based on etiological, epidemiological, anatomical, pathological, functional and morphological factors.

Classification

  • In 1974, an international committee of thyroid pathologists published the first WHO histological classification of thyroid tumours which had served as a basis for various clinical, pathological, and epidemiological studies. [1]
  • WHO Histological Classification of Thyroid Tumors, Second edition (1988) [1]
    • Epithelial tumors
      • Benign
        • Follicular adenoma
        • Others
      • Malignant
        • Follicular carcinoma
        • Papillary carcinoma
        • Medullary carcinoma
        • Undifferentiated (anaplastic) carcinoma
        • Others
    • Nonepithelial tumors
      • Benign
      • Malignant
    • Malignant lymphomas
    • Miscellaneous tumors
    • Secondary tumors
    • Unclassified tumors
    • Tumor-like lesions
  • Goiter may be also be classified according to various classification methods based on the following:
    • Etiological classification
    • Epidemiological classification
    • Anatomical classification
    • Pathological classification
    • Functional classification
    • Morphological classification
  • Etiological classification:
    • Physiological goitre: Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty
    • Pathological goitre: Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions
  • Epidemiological classification:
    • Familial goitres: Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis
    • Endemic goitres: Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality
    • Sporadic goitres: Goitres that run sporadically
  • Anatomical classification:
    • Cervical goitre: Goitre situated on the anterior aspect of the neck
    • Retrosternal goitre: Goitre extends downward and get situated behind the sternum
    • Intrathoracic goitre: The type of goitre which extends into thoracic cavity
  • Pathological classification:
    • Simple goitres
    • Toxic goitres
    • Neoplastic goitres
    • Inflammatory goitres
    • Miscellaneous (Other rare types)
  • Functional classification:
    • Toxic goitre: Type of goitre associated with thyroid hyperfunction (hyperthyroidism)
    • Non-toxic: Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid)
  • Morphological classification: According to the texture of the gland
    • Diffuse goitre
    • Nodular goitre
      • Solitary nodular goitre
      • Multinodular goitre

References

  1. ↑ 1.0 1.1 Hedinger C, Williams ED, Sobin LH (1989). "The WHO histological classification of thyroid tumors: a commentary on the second edition". Cancer. 63 (5): 908–11. PMID 2914297.

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