Goiter classification: Difference between revisions
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*'''<u>Etiological classification:</u>''' | *'''<u>Etiological classification:</u>''' | ||
**Physiological goitre: Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty | **'''Physiological goitre:''' Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty | ||
**Pathological goitre: Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions | **'''Pathological goitre:''' Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions | ||
*'''<u>Epidemiological classification:</u>''' | *'''<u>Epidemiological classification:</u>''' | ||
**Familial goitres: Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis | **'''Familial goitres:''' Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis | ||
**Endemic goitres: Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality | **'''Endemic goitres:''' Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality | ||
**Sporadic goitres: Goitres that run sporadically | **'''Sporadic goitres:''' Goitres that run sporadically | ||
*'''<u>Anatomical classification:</u>''' | *'''<u>Anatomical classification:</u>''' | ||
**Cervical goitre: Goitre situated on the anterior aspect of the neck | **'''Cervical goitre:''' Goitre situated on the anterior aspect of the neck | ||
**Retrosternal goitre: Goitre extends downward and | **'''Retrosternal goitre:''' Goitre extends downward and gets situated behind the sternum | ||
**Intrathoracic goitre: | **'''Intrathoracic goitre:''' Goitre which extends into thoracic cavity | ||
*'''<u>Pathological classification:</u>''' | *'''<u>Pathological classification:</u>''' | ||
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*'''<u>Functional classification:</u>''' | *'''<u>Functional classification:</u>''' | ||
**Toxic goitre: Type of goitre associated with thyroid hyperfunction (hyperthyroidism) | **'''Toxic goitre:''' Type of goitre associated with thyroid hyperfunction (hyperthyroidism) | ||
**Non-toxic: Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid) | **'''Non-toxic:''' Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid) | ||
*'''<u>Morphological classification:</u>''' According to the texture of the gland | *'''<u>Morphological classification:</u>''' According to the texture of the gland | ||
Revision as of 20:28, 12 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- In 1974, an international committee of thyroid pathologists published the first WHO histological classification of thyroid tumours which had served as a basis for various clinical, pathological, and epidemiological studies
- Goiter may also be classified according to various classification methods based on etiological, epidemiological, anatomical, pathological, functional and morphological factors.
Classification
- In 1974, an international committee of thyroid pathologists published the first WHO histological classification of thyroid tumours which had served as a basis for various clinical, pathological, and epidemiological studies. [1]
- WHO Histological Classification of Thyroid Tumors, Second edition (1988) [1]
- Epithelial tumors
- Benign
- Follicular adenoma
- Others
- Malignant
- Follicular carcinoma
- Papillary carcinoma
- Medullary carcinoma
- Undifferentiated (anaplastic) carcinoma
- Others
- Benign
- Nonepithelial tumors
- Benign
- Malignant
- Malignant lymphomas
- Miscellaneous tumors
- Secondary tumors
- Unclassified tumors
- Tumor-like lesions
- Epithelial tumors
- Goiter may be also be classified according to various classification methods based on the following criteria:
- Etiological classification
- Epidemiological classification
- Anatomical classification
- Pathological classification
- Functional classification
- Morphological classification
- Etiological classification:
- Physiological goitre: Goitres resulting from increased metabolic demand of thyroid hormones e.g. during pregnancy or puberty
- Pathological goitre: Goitres resulting from diseases affecting the thyroid gland e.g. Neoplastic or inflammatory conditions
- Epidemiological classification:
- Familial goitres: Goitres that run in families as a result of Inherited defect of thyroid hormone synthesis
- Endemic goitres: Defined as thyroid enlargement affecting a significant number of inhabitants of a particular locality
- Sporadic goitres: Goitres that run sporadically
- Anatomical classification:
- Cervical goitre: Goitre situated on the anterior aspect of the neck
- Retrosternal goitre: Goitre extends downward and gets situated behind the sternum
- Intrathoracic goitre: Goitre which extends into thoracic cavity
- Pathological classification:
- Simple goitres
- Toxic goitres
- Neoplastic goitres
- Inflammatory goitres
- Miscellaneous (Other rare types)
- Functional classification:
- Toxic goitre: Type of goitre associated with thyroid hyperfunction (hyperthyroidism)
- Non-toxic: Type of goitre associated with thyroid hypofunction (hypothyroidism) or normal thyroid function (Euthyroid)
- Morphological classification: According to the texture of the gland
- Diffuse goitre
- Nodular goitre
- Solitary nodular goitre
- Multinodular goitre