Hirsutism natural history, complications and prognosis: Difference between revisions
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===Natural History=== | ===Natural History=== | ||
* Age of onset | * Age of onset | ||
** Idiopathic hirsutism and the other less-serious causes of hirsutism usually begin at puberty. | ** [[Idiopathic]] hirsutism and the other less-serious causes of hirsutism usually begin at [[puberty]]. | ||
** Hirsutism that occurs in middle-aged or older women may suggest an | ** Hirsutism that occurs in middle-aged or older women may suggest an [[Adrenal gland|adrena]]<nowiki/>l or [[Ovarian tumor|ovarian tumo]]<nowiki/>r. | ||
* Family history: A patient with a family history of hirsutism is consistent with CAH; however, idiopathic hirsutism and polycystic ovary syndrome (PCOS) can also be familial. | * Family history: A patient with a family history of hirsutism is consistent with [[CAH]]; however, idiopathic hirsutism and [[polycystic ovary syndrome]] (PCOS) can also be [[familial]]. | ||
** Hirsutism severity and rate of progression | ** Hirsutism severity and rate of progression | ||
*** The history of a benign form of hirsutism is usually characterized by pubertal onset with slow progression over many years. This is often true of hirsutism with PCOS. | *** The history of a [[benign]] form of hirsutism is usually characterized by [[pubertal]] onset with slow progression over many years. This is often true of hirsutism with [[PCOS]]. | ||
*** When a history of rapid severe hirsutism or other signs of virilization are obtained, an androgen-secreting tumor is a possibility. | *** When a history of rapid severe hirsutism or other signs of [[virilization]] are obtained, an [[androgen]]-secreting tumor is a possibility. | ||
** Adrenarche and puberty | ** [[Adrenarche]] and [[puberty]] | ||
*** Because the development of pubic hair depends on adrenal androgens, early development points toward CAH. | *** Because the development of pubic hair depends on adrenal [[androgens]], early development points toward [[CAH]]. | ||
*** In contrast, ovarian hyperandrogenism is associated with normal adrenarche and delayed menarche or irregular | *** In contrast, ovarian [[hyperandrogenism]] is associated with normal [[adrenarche]] and delayed [[menarche]] or irregular [[Menses|mense]]<nowiki/>s.<ref name="urlHirsutism Clinical Presentation: History, Physical, Causes">{{cite web |url=http://emedicine.medscape.com/article/121038-clinical |title=Hirsutism Clinical Presentation: History, Physical, Causes |format= |work= |accessdate=}}</ref> | ||
===Complications=== | ===Complications=== | ||
===Prognosis=== | ===Prognosis=== | ||
Prognosis depends on the underlynig cause of the hirsutism and whether it is benign or malignant.<ref name="urlHirsutism: Background, Pathophysiology, Epidemiology">{{cite web |url=http://emedicine.medscape.com/article/121038-overview#a2 |title=Hirsutism: Background, Pathophysiology, Epidemiology |format= |work= |accessdate=}}</ref> | [[Prognosis]] depends on the underlynig cause of the hirsutism and whether it is [[benign]] or [[malignant]].<ref name="urlHirsutism: Background, Pathophysiology, Epidemiology">{{cite web |url=http://emedicine.medscape.com/article/121038-overview#a2 |title=Hirsutism: Background, Pathophysiology, Epidemiology |format= |work= |accessdate=}}</ref> | ||
==References== | ==References== | ||
Revision as of 15:40, 14 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Natural History, Complications and Prognosis
Natural History
- Age of onset
- Idiopathic hirsutism and the other less-serious causes of hirsutism usually begin at puberty.
- Hirsutism that occurs in middle-aged or older women may suggest an adrenal or ovarian tumor.
- Family history: A patient with a family history of hirsutism is consistent with CAH; however, idiopathic hirsutism and polycystic ovary syndrome (PCOS) can also be familial.
- Hirsutism severity and rate of progression
- The history of a benign form of hirsutism is usually characterized by pubertal onset with slow progression over many years. This is often true of hirsutism with PCOS.
- When a history of rapid severe hirsutism or other signs of virilization are obtained, an androgen-secreting tumor is a possibility.
- Adrenarche and puberty
- Because the development of pubic hair depends on adrenal androgens, early development points toward CAH.
- In contrast, ovarian hyperandrogenism is associated with normal adrenarche and delayed menarche or irregular menses.[1]
- Hirsutism severity and rate of progression
Complications
Prognosis
Prognosis depends on the underlynig cause of the hirsutism and whether it is benign or malignant.[2]