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{{‪Creutzfeldt-Jakob disease‬}}
{{‪Creutzfeldt-Jakob disease‬}}
{{CMG}}  
{{CMG}} {{AE}}{{MMJ}}
==Overview==
==Overview==
Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.


==Historical Perspective==
==Historical Perspective==
*Creutzfeldt Jakob disease was first described in 1920-1921 by two German [[neurologist]]s, [[Hans Gerhard Creutzfeldt]] and [[Alfons Maria Jakob]].
 
*The term ''Creutzfeldt Jakob'' was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob's report.<ref name="McKintosh-2003">{{Cite journal  | last1 = McKintosh | first1 = E. | last2 = Tabrizi | first2 = SJ. | last3 = Collinge | first3 = J. | title = Prion diseases. | journal = J Neurovirol | volume = 9 | issue = 2 | pages = 183-93 | month = Apr | year = 2003 | doi = 10.1080/13550280390194082 | PMID = 12707849 }}</ref>
* In 1997, [[Stanley B. Prusiner]] was awarded the Nobel Prize in physiology or medicine for his discovery of [[prion]]s.
*In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a [[virus]]-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human  Creutzfeldt Jakob disease agent.<ref name="Manuelidis2007">{{cite journal| author=Manuelidis L| coauthors=Yu ZX, Barquero N, Mullins B|date=February 6, 2007| title=Cells infected with scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles| journal=Proceedings of the National Academy of Science| volume=104| issue=6| pages=1975-1970| pmid=17267596|url=http://www.pnas.org/cgi/content/full/104/6/1965| accessdate=2007-09-24}}</ref>


==References==
==References==

Revision as of 16:09, 19 October 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.

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