HIV associated nephropathy causes: Difference between revisions
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Other factors that are attributed to the development of HIV-associated nephropathy is the use of intravenous drugs, however, this is inconclusive as patients with HIV-associated nephropathy are not all intravenous drug users.<ref name="pmid3599656">{{cite journal| author=Pardo V, Meneses R, Ossa L, Jaffe DJ, Strauss J, Roth D et al.| title=AIDS-related glomerulopathy: occurrence in specific risk groups. | journal=Kidney Int | year= 1987 | volume= 31 | issue= 5 | pages= 1167-73 | pmid=3599656 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3599656 }}</ref><ref name="pmid10469389">{{cite journal| author=Klotman PE| title=HIV-associated nephropathy. | journal=Kidney Int | year= 1999 | volume= 56 | issue= 3 | pages= 1161-76 | pmid=10469389 | doi=10.1046/j.1523-1755.1999.00748.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10469389 }}</ref><ref name="pmid3561458">{{cite journal| author=Rao TK, Friedman EA, Nicastri AD| title=The types of renal disease in the acquired immunodeficiency syndrome. | journal=N Engl J Med | year= 1987 | volume= 316 | issue= 17 | pages= 1062-8 | pmid=3561458 | doi=10.1056/NEJM198704233161705 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3561458 }}</ref> | Other factors that are attributed to the development of HIV-associated nephropathy is the use of intravenous drugs, however, this is inconclusive as patients with HIV-associated nephropathy are not all intravenous drug users.<ref name="pmid3599656">{{cite journal| author=Pardo V, Meneses R, Ossa L, Jaffe DJ, Strauss J, Roth D et al.| title=AIDS-related glomerulopathy: occurrence in specific risk groups. | journal=Kidney Int | year= 1987 | volume= 31 | issue= 5 | pages= 1167-73 | pmid=3599656 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3599656 }}</ref><ref name="pmid10469389">{{cite journal| author=Klotman PE| title=HIV-associated nephropathy. | journal=Kidney Int | year= 1999 | volume= 56 | issue= 3 | pages= 1161-76 | pmid=10469389 | doi=10.1046/j.1523-1755.1999.00748.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10469389 }}</ref><ref name="pmid3561458">{{cite journal| author=Rao TK, Friedman EA, Nicastri AD| title=The types of renal disease in the acquired immunodeficiency syndrome. | journal=N Engl J Med | year= 1987 | volume= 316 | issue= 17 | pages= 1062-8 | pmid=3561458 | doi=10.1056/NEJM198704233161705 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3561458 }}</ref> | ||
High risk alleles G1 (a missense mutation) and G2 (a frameshift deletion) for Apolipoprotein 1 (APOL1) are associated with HIVAN (APOL1 gene is on chromosome 22). | |||
==References== | ==References== | ||
Revision as of 16:05, 29 June 2020
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Differentiating HIV associated nephropathy from other Diseases |
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HIV associated nephropathy causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2];Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
Currently there are no known established causes of HIV-associated nephropathy. However, the genetic component, a key to the pathogenesis of the disease in blacks but not in other races is a factor that is seen in HIV-associated nephropathy.[1]
Causes
Currently there are no known established causes of HIV-associated nephropathy. However, the genetic component, a key to the pathogenesis of the disease in blacks but not in other races is a factor that is seen in HIV-associated nephropathy.[2] Another cause for HIV-associated nephropathy is the lack of a deletion mutation of CCR5 or CCR2, which is protective form HIV-1 infection.[3]
Other factors that are attributed to the development of HIV-associated nephropathy is the use of intravenous drugs, however, this is inconclusive as patients with HIV-associated nephropathy are not all intravenous drug users.[4][5][6]
High risk alleles G1 (a missense mutation) and G2 (a frameshift deletion) for Apolipoprotein 1 (APOL1) are associated with HIVAN (APOL1 gene is on chromosome 22).
References
- ↑ Klotman PE (1999). "HIV-associated nephropathy". Kidney Int. 56 (3): 1161–76. doi:10.1046/j.1523-1755.1999.00748.x. PMID 10469389.
- ↑ Klotman PE (1999). "HIV-associated nephropathy". Kidney Int. 56 (3): 1161–76. doi:10.1046/j.1523-1755.1999.00748.x. PMID 10469389.
- ↑ Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R; et al. (1996). "Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection". Cell. 86 (3): 367–77. PMID 8756719.
- ↑ Pardo V, Meneses R, Ossa L, Jaffe DJ, Strauss J, Roth D; et al. (1987). "AIDS-related glomerulopathy: occurrence in specific risk groups". Kidney Int. 31 (5): 1167–73. PMID 3599656.
- ↑ Klotman PE (1999). "HIV-associated nephropathy". Kidney Int. 56 (3): 1161–76. doi:10.1046/j.1523-1755.1999.00748.x. PMID 10469389.
- ↑ Rao TK, Friedman EA, Nicastri AD (1987). "The types of renal disease in the acquired immunodeficiency syndrome". N Engl J Med. 316 (17): 1062–8. doi:10.1056/NEJM198704233161705. PMID 3561458.