Pseudohypoparathyroidism classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]

Overview

Pseudohypoparathyroidism(PTH) is classified based on the measurement of serum and urinary cAMP and phosphate excretion levels after the injection of biologically active parathyroid hormone into pseudohypoparathyroidism type I and pseudohypoparathyroidism type II.

Classification

• Pseudohypoparathyroidism is classified based on the measurement of serum and urinary cAMP and phosphate excretion levels after the injection of biologically active parathyroid hormone into following types:
  • Pseudohypoparathyroidism type I
  • Pseudohypoparathyroidism type II

• Pseudohypoparathyroidism type 1 is further classified into following subtype:
  • Pseudohypoparathyroidism type 1a
  • Pseudohypoparathyroidism type 1b
  • Pseudohypoparathyroidism type 1c.
  • Pseudopseudohypoparathyroidism
• Other forms of parathyroid hormone resistance include :
  • Blomstrand Syndrome
  • Acrodysostosis type 1 
  • Acrodysostosis type 2 

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