Toxic megacolon natural history, complications and prognosis: Difference between revisions
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===Prognosis=== | ===Prognosis=== | ||
*Depending on the presence of the perforation at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent without perforation.<ref name="pmid6691535">{{cite journal |vauthors=Grant CS, Dozois RR |title=Toxic megacolon: ultimate fate of patients after successful medical management |journal=Am. J. Surg. |volume=147 |issue=1 |pages=106–10 |year=1984 |pmid=6691535 |doi= |url=}}</ref> | *Depending on the presence of the perforation at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent without perforation.<ref name="pmid6691535">{{cite journal |vauthors=Grant CS, Dozois RR |title=Toxic megacolon: ultimate fate of patients after successful medical management |journal=Am. J. Surg. |volume=147 |issue=1 |pages=106–10 |year=1984 |pmid=6691535 |doi= |url=}}</ref><ref name="pmid7555415">{{cite journal |vauthors=Trudel JL, Deschênes M, Mayrand S, Barkun AN |title=Toxic megacolon complicating pseudomembranous enterocolitis |journal=Dis. Colon Rectum |volume=38 |issue=10 |pages=1033–8 |year=1995 |pmid=7555415 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of toxic megacolon include:
- Perforation or opening in the wall of the colon
- Bleeding
- Shock
- Sepsis
Prognosis
- Depending on the presence of the perforation at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent without perforation.[1][2]
References
- ↑ Grant CS, Dozois RR (1984). "Toxic megacolon: ultimate fate of patients after successful medical management". Am. J. Surg. 147 (1): 106–10. PMID 6691535.
- ↑ Trudel JL, Deschênes M, Mayrand S, Barkun AN (1995). "Toxic megacolon complicating pseudomembranous enterocolitis". Dis. Colon Rectum. 38 (10): 1033–8. PMID 7555415.