Toxic megacolon natural history, complications and prognosis: Difference between revisions
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===Complications=== | ===Complications=== | ||
*Common complications of toxic megacolon include:<ref name="pmid22009735">{{cite journal |vauthors=Autenrieth DM, Baumgart DC |title=Toxic megacolon |journal=Inflamm. Bowel Dis. |volume=18 |issue=3 |pages=584–91 |year=2012 |pmid=22009735 |doi=10.1002/ibd.21847 |url=}}</ref> | *Common complications of toxic megacolon include:<ref name="pmid22009735">{{cite journal |vauthors=Autenrieth DM, Baumgart DC |title=Toxic megacolon |journal=Inflamm. Bowel Dis. |volume=18 |issue=3 |pages=584–91 |year=2012 |pmid=22009735 |doi=10.1002/ibd.21847 |url=}}</ref><ref name="Sayedy2010">{{cite journal|last1=Sayedy|first1=Leena|title=Toxic megacolon associatedClostridium difficilecolitis|journal=World Journal of Gastrointestinal Endoscopy|volume=2|issue=8|year=2010|pages=293|issn=1948-5190|doi=10.4253/wjge.v2.i8.293}}</ref> | ||
**Perforation or opening in the wall of the colon | **Perforation or opening in the wall of the colon | ||
**Bleeding | **Bleeding | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of toxic megacolon include:[1][2]
- Perforation or opening in the wall of the colon
- Bleeding
- Shock
- Sepsis
Prognosis
- Depending on the presence of the perforation at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent without perforation.[3][4]
References
- ↑ Autenrieth DM, Baumgart DC (2012). "Toxic megacolon". Inflamm. Bowel Dis. 18 (3): 584–91. doi:10.1002/ibd.21847. PMID 22009735.
- ↑ Sayedy, Leena (2010). "Toxic megacolon associatedClostridium difficilecolitis". World Journal of Gastrointestinal Endoscopy. 2 (8): 293. doi:10.4253/wjge.v2.i8.293. ISSN 1948-5190.
- ↑ Grant CS, Dozois RR (1984). "Toxic megacolon: ultimate fate of patients after successful medical management". Am. J. Surg. 147 (1): 106–10. PMID 6691535.
- ↑ Trudel JL, Deschênes M, Mayrand S, Barkun AN (1995). "Toxic megacolon complicating pseudomembranous enterocolitis". Dis. Colon Rectum. 38 (10): 1033–8. PMID 7555415.