Mantle cell lymphoma laboratory findings: Difference between revisions
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{{ Mantle cell lymphoma }} | {{ Mantle cell lymphoma }} | ||
{{CMG}}; {{AE}} {{AS}} | {{CMG}}; {{AE}} {{Akram}} {{AS}} | ||
==Overview== | ==Overview== | ||
Laboratory tests for mantle cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[cytogenetic analysis]], [[flow cytometry]], [[immunohistochemistry]], [[genetic testing]], [[FISH]], [[PCR]], and [[immunophenotyping]]. | Laboratory tests for mantle cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[cytogenetic analysis]], [[flow cytometry]], [[immunohistochemistry]], [[genetic testing]], [[FISH]], [[PCR]], and [[immunophenotyping]]. | ||
==Laboratory tests== | ==Laboratory tests== | ||
Laboratory tests for mantle cell lymphoma include:<ref name=”seer”>National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref> | Laboratory tests for mantle cell lymphoma include:<ref name=”seer”>National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref> | ||
* [[Complete blood count]] (CBC) | * [[Complete blood count]] (CBC) with differential count | ||
* Blood chemistry studies | * Blood chemistry studies | ||
* [[Cytogenetic analysis]] | * [[Cytogenetic analysis]] | ||
Revision as of 19:41, 3 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ali Akram, M.B.B.S.[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
Laboratory tests for mantle cell lymphoma include complete blood count (CBC), blood chemistry studies, cytogenetic analysis, flow cytometry, immunohistochemistry, genetic testing, FISH, PCR, and immunophenotyping.
Laboratory tests
Laboratory tests for mantle cell lymphoma include:[1]
- Complete blood count (CBC) with differential count
- Blood chemistry studies
- Cytogenetic analysis
- Flow cytometry
- Immunohistochemistry
- Genetic testing
- Heavy and light chain genes rearranged, t(11;14)(q13;q32) in virtually all cases
- Overexpression CYCLIN D mRNA
- Mutation or deletions of ATM gene
- Polymerase chain reaction (PCR) and CER3 clonotypic primers are additional methods, but are less often used.
References
- ↑ National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov