Nasopharyngeal carcinoma classification: Difference between revisions
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{{Nasopharyngeal carcinoma}} | {{Nasopharyngeal carcinoma}} | ||
{{CMG}}{{Faizan}} | {{CMG}}{{AE}}{{Homa}}{{Faizan}} | ||
==Overview== | ==Overview== | ||
[[Nasopharyngeal carcinoma]] may be classified according to [[microscopic]] features into 3 subtypes: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma, and undifferentiated type. | [[Nasopharyngeal carcinoma]] may be classified according to [[microscopic]] features into 3 subtypes: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma, and undifferentiated type. | ||
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==Classification== | ==Classification== | ||
===Histologic classification=== | ===Histologic classification=== | ||
World Health Classification (2005) for NPC:<ref name= Librepathology>Nasopharyngeal carcinoma | World Health Classification (2005) for NPC:<ref name= Librepathology>Nasopharyngeal carcinoma | ||
{| class="wikitable" | {| class="wikitable" | ||
! Type | ! Type |
Revision as of 15:54, 19 February 2019
Nasopharyngeal carcinoma Microchapters |
Differentiating Nasopharyngeal carcinoma from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Nasopharyngeal carcinoma classification On the Web |
American Roentgen Ray Society Images of Nasopharyngeal carcinoma classification |
Risk calculators and risk factors for Nasopharyngeal carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]
Overview
Nasopharyngeal carcinoma may be classified according to microscopic features into 3 subtypes: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma, and undifferentiated type.
Classification
Histologic classification
World Health Classification (2005) for NPC:<ref name= Librepathology>Nasopharyngeal carcinoma
Type | Histology | Description | EBV | Prevalence | Prognosis |
---|---|---|---|---|---|
1 | Keratinizing SCC | graded poorly-well-differentiated | -ve | bad | |
2a | Nonkeratinizing carcinoma, differentiated | well defined cell borders & tumor nest borders | +ve | good | |
2b | Nonkeratinizing carcinoma, undifferentiated | sheets/syncytial, vescicular nuclei, prominent nucleoli, pink cytoplasm | most common | ||
3 | Basaloid SCC | mimics basal cell carcinoma | least common |