Esophageal cancer diagnostic study of choice: Difference between revisions
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== Diagnostic Study of Choice == | == Diagnostic Study of Choice == | ||
=== Gold standard/Study of choice: === | |||
* Endoscopic biopsy is the gold standard test for the diagnosis of esophageal cancer. | * Endoscopic biopsy is the gold standard test for the diagnosis of esophageal cancer. | ||
* The following | *The following result of endoscopic biopsy is a confirmatory of esophageal cancer: | ||
**friable lesion | |||
**superficial plaques | **superficial plaques | ||
**superfcial nodules | **superfcial nodules | ||
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**circumferential masses | **circumferential masses | ||
**large ulcerations<ref name="pmid9934727">{{cite journal |vauthors=Lightdale CJ |title=Esophageal cancer. American College of Gastroenterology |journal=Am. J. Gastroenterol. |volume=94 |issue=1 |pages=20–9 |year=1999 |pmid=9934727 |doi=10.1111/j.1572-0241.1999.00767.x |url=}}</ref><ref name="pmid19117343">{{cite journal |vauthors=Yendamuri S, Swisher SG, Correa AM, Hofstetter W, Ajani JA, Francis A, Maru D, Mehran RJ, Rice DC, Roth JA, Walsh GL, Vaporciyan AA |title=Esophageal tumor length is independently associated with long-term survival |journal=Cancer |volume=115 |issue=3 |pages=508–16 |year=2009 |pmid=19117343 |doi=10.1002/cncr.24062 |url=}}</ref> | **large ulcerations<ref name="pmid9934727">{{cite journal |vauthors=Lightdale CJ |title=Esophageal cancer. American College of Gastroenterology |journal=Am. J. Gastroenterol. |volume=94 |issue=1 |pages=20–9 |year=1999 |pmid=9934727 |doi=10.1111/j.1572-0241.1999.00767.x |url=}}</ref><ref name="pmid19117343">{{cite journal |vauthors=Yendamuri S, Swisher SG, Correa AM, Hofstetter W, Ajani JA, Francis A, Maru D, Mehran RJ, Rice DC, Roth JA, Walsh GL, Vaporciyan AA |title=Esophageal tumor length is independently associated with long-term survival |journal=Cancer |volume=115 |issue=3 |pages=508–16 |year=2009 |pmid=19117343 |doi=10.1002/cncr.24062 |url=}}</ref> | ||
**Even though large masses seen in the esophagus are almost pathognomonic for esophageal cancer, the diagnosis of squamous cell carcinoma or adenocarcinoma esophageal cancer is confirmed by biopsy. | |||
Even though large masses seen in the esophagus are almost pathognomonic for esophageal cancer, the diagnosis of squamous cell carcinoma or adenocarcinoma esophageal cancer is confirmed by biopsy. | |||
==== The comparison table for diagnostic studies of choice for esophageal cancer ==== | ==== The comparison table for diagnostic studies of choice for esophageal cancer ==== | ||
Revision as of 15:27, 12 December 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
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Overview
Esophageal cancer is best diagnosed using an endoscope to visualize the esophageal lesion, followed by a biopsy to confirm the diagnosis. These are done within the same sitting.
Diagnostic Study of Choice
Gold standard/Study of choice:
- Endoscopic biopsy is the gold standard test for the diagnosis of esophageal cancer.
- The following result of endoscopic biopsy is a confirmatory of esophageal cancer:
- friable lesion
- superficial plaques
- superfcial nodules
- superficial ulcerations
- strictures
- ulcerated masses
- circumferential masses
- large ulcerations[1][2]
- Even though large masses seen in the esophagus are almost pathognomonic for esophageal cancer, the diagnosis of squamous cell carcinoma or adenocarcinoma esophageal cancer is confirmed by biopsy.
The comparison table for diagnostic studies of choice for esophageal cancer
- Studies have found that the greater the number of biopsies taken (up to seven), the higher the diagnostic accuracy. The addition of brush cytology specimens to seven biopsies increased the accuracy to 100%.[3]
| Sensitivity | Specificity | |
|---|---|---|
| Endoscopic biopsy | 90% | 95% |
References
- ↑ Lightdale CJ (1999). "Esophageal cancer. American College of Gastroenterology". Am. J. Gastroenterol. 94 (1): 20–9. doi:10.1111/j.1572-0241.1999.00767.x. PMID 9934727.
- ↑ Yendamuri S, Swisher SG, Correa AM, Hofstetter W, Ajani JA, Francis A, Maru D, Mehran RJ, Rice DC, Roth JA, Walsh GL, Vaporciyan AA (2009). "Esophageal tumor length is independently associated with long-term survival". Cancer. 115 (3): 508–16. doi:10.1002/cncr.24062. PMID 19117343.
- ↑ Graham DY, Schwartz JT, Cain GD, Gyorkey F (1982). "Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma". Gastroenterology. 82 (2): 228–31. PMID 7054024.