SNX21: Difference between revisions
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'''Sorting nexin-21''' is a [[protein]] that in humans is encoded by the ''SNX21'' [[gene]].<ref name="pmid12461558">{{cite journal | vauthors = Worby CA, Dixon JE | title = Sorting out the cellular functions of sorting nexins | journal = Nat Rev Mol Cell Biol | volume = 3 | issue = 12 | pages = 919–31 |date=Dec 2002 | pmid = 12461558 | pmc = | doi = 10.1038/nrm974 }}</ref><ref name="pmid12459172">{{cite journal | vauthors = Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M | title = Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development | journal = Biochem Biophys Res Commun | volume = 299 | issue = 4 | pages = 542–8 |date=Dec 2002 | pmid = 12459172 | pmc = | doi =10.1016/S0006-291X(02)02695-5 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNX21 sorting nexin family member 21| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90203| accessdate = }}</ref> | '''Sorting nexin-21''' is a [[protein]] that in humans is encoded by the ''SNX21'' [[gene]].<ref name="pmid12461558">{{cite journal | vauthors = Worby CA, Dixon JE | title = Sorting out the cellular functions of sorting nexins | journal = Nat Rev Mol Cell Biol | volume = 3 | issue = 12 | pages = 919–31 |date=Dec 2002 | pmid = 12461558 | pmc = | doi = 10.1038/nrm974 }}</ref><ref name="pmid12459172">{{cite journal | vauthors = Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M | title = Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development | journal = Biochem Biophys Res Commun | volume = 299 | issue = 4 | pages = 542–8 |date=Dec 2002 | pmid = 12459172 | pmc = | doi =10.1016/S0006-291X(02)02695-5 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNX21 sorting nexin family member 21| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90203| accessdate = }}</ref> | ||
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{{PBB_Summary | {{PBB_Summary | ||
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| summary_text = This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.<ref name="entrez" /> | | summary_text = This gene encodes a member of the [[sorting nexin]] family. Members of this family contain a [[phosphinooxazolines|phox]] (PX) domain, which is a [[phosphoinositide]] binding domain, and are involved in intracellular trafficking. This protein does not contain a [[coiled coil]] region, like some family members. The specific function of this protein has not been determined. Multiple [[transcript variants]] encoding distinct [[isoforms]] have been identified for this gene.<ref name="entrez" /> | ||
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Sorting nexin-21 is a protein that in humans is encoded by the SNX21 gene.[1][2][3]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[3]
References
- ↑ Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558.
- ↑ Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M (Dec 2002). "Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development". Biochem Biophys Res Commun. 299 (4): 542–8. doi:10.1016/S0006-291X(02)02695-5. PMID 12459172.
- ↑ 3.0 3.1 "Entrez Gene: SNX21 sorting nexin family member 21".
Further reading
- Xu Y, Seet LF, Hanson B, Hong W (2002). "The Phox homology (PX) domain, a new player in phosphoinositide signalling". Biochem. J. 360 (Pt 3): 513–30. doi:10.1042/0264-6021:3600513. PMC 1222253. PMID 11736640.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
- Teasdale RD, Loci D, Houghton F, et al. (2001). "A large family of endosome-localized proteins related to sorting nexin 1". Biochem. J. 358 (Pt 1): 7–16. doi:10.1042/0264-6021:3580007. PMC 1222026. PMID 11485546.
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