SNAG1: Difference between revisions
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'''Sorting nexin-18''' is a [[protein]] that in humans is encoded by the ''SNX18'' [[gene]].<ref name="pmid16782399">{{cite journal | vauthors = Seet LF, Hong W | title = The Phox (PX) domain proteins and membrane traffic | journal = Biochim Biophys Acta | volume = 1761 | issue = 8 | pages = 878–96 |date=Sep 2006 | pmid = 16782399 | pmc = | doi = 10.1016/j.bbalip.2006.04.011 }}</ref><ref name="pmid17761170">{{cite journal | vauthors = Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J | title = A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells | journal = FEBS Lett | volume = 581 | issue = 23 | pages = 4455–62 |date=Sep 2007 | pmid = 17761170 | pmc = | doi = 10.1016/j.febslet.2007.08.025 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574| accessdate = }}</ref> | '''Sorting nexin-18''' is a [[protein]] that in humans is encoded by the ''SNX18'' [[gene]].<ref name="pmid16782399">{{cite journal | vauthors = Seet LF, Hong W | title = The Phox (PX) domain proteins and membrane traffic | journal = Biochim Biophys Acta | volume = 1761 | issue = 8 | pages = 878–96 |date=Sep 2006 | pmid = 16782399 | pmc = | doi = 10.1016/j.bbalip.2006.04.011 }}</ref><ref name="pmid17761170">{{cite journal | vauthors = Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J | title = A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells | journal = FEBS Lett | volume = 581 | issue = 23 | pages = 4455–62 |date=Sep 2007 | pmid = 17761170 | pmc = | doi = 10.1016/j.febslet.2007.08.025 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574| accessdate = }}</ref> | ||
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{{PBB_Summary | {{PBB_Summary | ||
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| summary_text = This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.<ref name="entrez">{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574| accessdate = }}</ref> | | summary_text = This gene encodes a member of the [[sorting nexin]] family. Members of this family contain a [[phosphinooxazolines|phox]] (PX) domain, which is a [[phosphoinositide]] binding domain, and are involved in intracellular trafficking. This protein does not contain a [[coiled coil]] region, like some family members, but contains a [[SH3 domain]]. The specific function of this protein has not been determined.<ref name="entrez">{{cite web | title = Entrez Gene: SNAG1 sorting nexin associated golgi protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=112574| accessdate = }}</ref> | ||
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Latest revision as of 19:00, 20 February 2018
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Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.[1][2][3]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.[3]
References
- ↑ Seet LF, Hong W (Sep 2006). "The Phox (PX) domain proteins and membrane traffic". Biochim Biophys Acta. 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399.
- ↑ Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J (Sep 2007). "A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells". FEBS Lett. 581 (23): 4455–62. doi:10.1016/j.febslet.2007.08.025. PMID 17761170.
- ↑ 3.0 3.1 "Entrez Gene: SNAG1 sorting nexin associated golgi protein 1".
Further reading
- Worby CA, Dixon JE (2003). "Sorting out the cellular functions of sorting nexins". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558.
- Xu Y, Seet LF, Hanson B, Hong W (2002). "The Phox homology (PX) domain, a new player in phosphoinositide signalling". Biochem. J. 360 (Pt 3): 513–30. doi:10.1042/0264-6021:3600513. PMC 1222253. PMID 11736640.
- Ozyildirim AM, Wistow GJ, Gao J, et al. (2005). "The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts". Invest. Ophthalmol. Vis. Sci. 46 (5): 1572–80. doi:10.1167/iovs.04-1380. PMID 15851553.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Schulze WX, Mann M (2004). "A novel proteomic screen for peptide-protein interactions". J. Biol. Chem. 279 (11): 10756–64. doi:10.1074/jbc.M309909200. PMID 14679214.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Teasdale RD, Loci D, Houghton F, et al. (2001). "A large family of endosome-localized proteins related to sorting nexin 1". Biochem. J. 358 (Pt 1): 7–16. doi:10.1042/0264-6021:3580007. PMC 1222026. PMID 11485546.
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