Autoimmune hepatitis risk factors: Difference between revisions
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{{CMG}}; {{AE}}:{{MKK}} | {{CMG}}; {{AE}}:{{MKK}} | ||
==Overview== | ==Overview== | ||
Common risk factors in the development of Autoimmune hepatitis include female gender, Genetic predisposition associated with HLADR3 and HLADR4, and | Common risk factors in the development of Autoimmune hepatitis include female gender, Genetic predisposition associated with HLADR3 and HLADR4, and History of other autoimmune hepatitis | ||
==Risk Factors== | ==Risk Factors== | ||
Revision as of 00:19, 28 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: :Manpreet Kaur, MD [2]
Overview
Common risk factors in the development of Autoimmune hepatitis include female gender, Genetic predisposition associated with HLADR3 and HLADR4, and History of other autoimmune hepatitis
Risk Factors
Common Risk Factors
Common risk factors in the development of Autoimmune hepatitis include:
- Females:
- Autoimmune hepatitis is more common in young females
- Genetic predisposition:[1]
- Autoimmune hepatitis type 1 has the association with HLA-DR3 and HLA-DR4
- Type 2 AIH has an association with the HLA-DQB1 and HLA-DRB1 alleles
- History of another autoimmune disease:
- Autoimmune diseases, including thyroiditis, type 1 diabetes, ulcerative colitis, celiac disease, and rheumatoid arthritis
Less Common Risk Factors
Less common risk factors in the development of Autoimmune hepatitis include:
- A history of viral infections:[2][3]
- Autoimmune hepatitis is common who are infected with the measles, herpes simplex or Epstein-Barr virus and hepatitis A, B or C infection in the past.
- History of drug intake:
- Minocycline, Nitrofurantoin, Hydralazine, Methyldopa Statins, Fenofibrate, Interferon, Infliximab, Etanercept increases the risk of autoimmune hepatitis
References
- ↑ Donaldson PT (2004). "Genetics of autoimmune and viral liver diseases; understanding the issues". J. Hepatol. 41 (2): 327–32. doi:10.1016/j.jhep.2004.06.001. PMID 15288484.
- ↑ Vento S, Cainelli F (2004). "Is there a role for viruses in triggering autoimmune hepatitis?". Autoimmun Rev. 3 (1): 61–9. doi:10.1016/S1568-9972(03)00053-3. PMID 14871651.
- ↑ Huppertz HI, Treichel U, Gassel AM, Jeschke R, Meyer zum Büschenfelde KH (1995). "Autoimmune hepatitis following hepatitis A virus infection". J. Hepatol. 23 (2): 204–8. PMID 7499793.