Multiple sclerosis classification: Difference between revisions
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In recent studies a new subtype recognized and named: '''clinically isolated syndrome (CIS)'''. It is when the clinical presentation of a disease is suggestive of myelin sheet inflammation but cannot fulfill the diagnostic criteria of MS.<ref name="pmid24871874">{{cite journal |vauthors=Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH |title=Defining the clinical course of multiple sclerosis: the 2013 revisions |journal=Neurology |volume=83 |issue=3 |pages=278–86 |year=2014 |pmid=24871874 |pmc=4117366 |doi=10.1212/WNL.0000000000000560 |url=}}</ref> | In recent studies a new subtype recognized and named: '''clinically isolated syndrome (CIS)'''. It is when the clinical presentation of a disease is suggestive of myelin sheet inflammation but cannot fulfill the diagnostic criteria of MS.<ref name="pmid24871874">{{cite journal |vauthors=Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH |title=Defining the clinical course of multiple sclerosis: the 2013 revisions |journal=Neurology |volume=83 |issue=3 |pages=278–86 |year=2014 |pmid=24871874 |pmc=4117366 |doi=10.1212/WNL.0000000000000560 |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 10:38, 21 January 2018
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Multiple sclerosis classification On the Web |
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Risk calculators and risk factors for Multiple sclerosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Multiple sclerosis may be classified according to clinical course into four groups:[1]
- Relapsing-remitting:
RRMS is defined by acute attacks of neurological dysfunction followed by full or partial recovery. Patient clinical symptoms are stable between the attacks.[1]
- Secondary progressive:
Patient with long term RRMS can switch to SPMS, when the neurological symptoms progressively worsen between the attacks.[1]
- Primary progressive:
PPMS is defined by continuously worsening of neurological dysfunction with no distinct attacks and remissions.[1]
- Progressive relapsing:
PRMS is defined by progression of disease from the beginning with acute attack episodes.[1]
These subtypes were defined In 1996 by the US National Multiple Sclerosis Society (NMSS).[1]
In recent studies a new subtype recognized and named: clinically isolated syndrome (CIS). It is when the clinical presentation of a disease is suggestive of myelin sheet inflammation but cannot fulfill the diagnostic criteria of MS.[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Lublin FD; Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996 Apr;46(4):907-11. PMID 8780061
- ↑ Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH (2014). "Defining the clinical course of multiple sclerosis: the 2013 revisions". Neurology. 83 (3): 278–86. doi:10.1212/WNL.0000000000000560. PMC 4117366. PMID 24871874.