Liver mass classification: Difference between revisions

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Revision as of 17:23, 1 February 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

A liver mass may be classified into several sub-types based on number of nodules, type of histo-pathology, and consistency.

A liver mass may be classified into several sub-types based on number of nodules, type of histo-pathology, and consistency.^[1]

Based on the number of nodules diagnosed on imaging liver mass can be classified into 2 types.
- Solitary nodule
- Multiple nodules
Based on the type of histo-pathology liver mass can be classified into 2 types.
- Benign
- Malignant
Based on the consitency of the mass, liver mass can be classified into 2 types.
- Complex cysts
- Simple cysts
Clinically a liver mass can be classified into 3 catogeries
- Benign mass lesions for which no treatment is needed
- Benign mass lesions for which treatment is needed
- Malignant mass lesions for which treatment is always required

Liver mass

Based on number of nodules

Type of histopathology

Imaging/consistency

Solitary

Multiple

Benign

Malignant

Simple

Cystic

WHO Classification of Liver Tumors
Benign Tumors			Malignant Tumors
Epithelial	Hepatocytes	Focal nodular hyperplasia Hepatocellular adenoma	HCC Fibrolamellar carcinoma Hepatoblastoma Carcinosarcoma
Epithelial	Biliary cells	Intrahepatic bileduct adenoma Intrahepatic bileduct cystadenoma Biliary papillomatosis	Cystadenocarcinoma Cholangiocarcinoma
Non-Epithelial	Mesenchymal	Hemangioma Lymphangioma Lymphangiomatosis Angiomyolipoma Infantile Hemangioma	Hemangioendothelioma Primary lymphoma Angiosarcoma Epitheloid

Classification of Hepatic Cysts
Simple cysts Multiple cysts arising in the setting of polycystic liver disease (PCLD) Parasitic cysts Cystic tumors Cystadenoma, cystadenocarcinoma, squamous cell carcinoma Abscesses

The table below summarizes the classification of common liver masses according to histopathological origin.


Classification of liver mass
Benign	Malignant
Hepatic hemangioma Focal nodular hyperplasia Hepatic adenoma Idiopathic noncirrhotic portal hypertension Nodular regenerative hyperplasia Angiolipoma Biliary cystadenoma Regenerative nodules	Hepatocellular carcinoma Cholangiocarcinoma Metastatic disease Angiosarcoma Cystadenocarcinoma Primary lymphoma

↑ Mergo PJ, Ros PR. Benign Lesions of the Liver. In: The Radiologic Clinics of North America, 2, W.B. Saunders, Philadelphia 1998. Vol 36, p.319.

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 ** Complex cysts
 ** Simple cysts
+* Clinically a liver mass can be classified into 3 catogeries
+** Benign mass lesions for which no treatment is needed
+** Benign mass lesions for which treatment is needed
+** Malignant mass lesions for which treatment is always required
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 {{familytree | | | | | | | | | | | | | | | | | A01 | | | | | | | | | | |A01=Liver mass}}
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-=== WHO classification of liver tumors ===
+=== <u>WHO classification of liver tumors</u> ===
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 ! colspan="4" style="background:#efefef;" |WHO Classification of Liver Tumors
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-=== Classification of Hepatic cysts ===
+=== <u>Classification of Hepatic cysts</u> ===
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 ! style="background:#efefef;" |Classification of Hepatic Cysts