Primary biliary cirrhosis surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

The mainstay of treatment for primary primarybiliary cirrhosis is medical therapy. Surgery is usually reserved for patients with either decompensated cirrhosis and endstage liver failure who do not show any improvement with medical therapy.

Surgery

• The mainstay of treatment for primarybiliary cirrhosis is medical therapy. Liver transplantation is usually reserved for patients with either:
  • Decompensated cirrhosis
  • Endstage liver failure:
    • Refractory ascites
    • Recurrent spontaneous bacterial peritonitis
    • Recurrent variceal hemorrhage
    • Hepatic encephalopathy
    • Hepatorenal syndrome type I
    • Hepatocellular carcinoma

Indications

Indications for liver transplantation include:

• Decompensated cirrhosis
• Endstage liver failure:
  • Refractory ascites
  • Recurrent spontaneous bacterial peritonitis
  • Recurrent variceal hemorrhage
  • Hepatic encephalopathy
  • Hepatorenal syndrome type I
  • Hepatocellular carcinoma