Primary biliary cirrhosis causes: Difference between revisions
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==Overview== | ==Overview== | ||
The cause of primary biliary cirrhosis has not been identified. However, it is thought that [[Autoimmunity|hyper-functioning immune system]] attributed to [[genetic predisposition]] is thought to have a role in causing primary biliary cirrhosis. Few environmental factors such as cigarette smoking, [[infections]] and chemical exposure have also known to play a role in causing primary biliary cirrhosis. | The cause of primary biliary cirrhosis has not been identified. However, it is thought that [[Autoimmunity|hyper-functioning immune system]] attributed to [[genetic predisposition]] is thought to have a role in causing primary biliary cirrhosis. Few environmental factors such as [[cigarette smoking]], [[infections]] and chemical exposure have also known to play a role in causing primary biliary cirrhosis. | ||
==Causes== | ==Causes== | ||
*The cause of primary biliary cirrhosis has not been identified. However, it is thought that [[Autoimmunity|hyper-functioning immune system]] attributed to [[genetic predisposition]] is thought to have a role in causing primary biliary cirrhosis.<ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546 }} </ref><ref name="pmid21529926">{{cite journal| author=Selmi C, Bowlus CL, Gershwin ME, Coppel RL| title=Primary biliary cirrhosis. | journal=Lancet | year= 2011 | volume= 377 | issue= 9777 | pages= 1600-9 | pmid=21529926 | doi=10.1016/S0140-6736(10)61965-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21529926 }} </ref><ref name="pmid25057950">{{cite journal| author=Juran BD, Lazaridis KN| title=Environmental factors in primary biliary cirrhosis. | journal=Semin Liver Dis | year= 2014 | volume= 34 | issue= 3 | pages= 265-72 | pmid=25057950 | doi=10.1055/s-0034-1383726 | pmc=4232304 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25057950 }} </ref> | *The cause of primary biliary cirrhosis has not been identified. However, it is thought that [[Autoimmunity|hyper-functioning immune system]] attributed to [[genetic predisposition]] is thought to have a role in causing primary biliary cirrhosis.<ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546 }} </ref><ref name="pmid21529926">{{cite journal| author=Selmi C, Bowlus CL, Gershwin ME, Coppel RL| title=Primary biliary cirrhosis. | journal=Lancet | year= 2011 | volume= 377 | issue= 9777 | pages= 1600-9 | pmid=21529926 | doi=10.1016/S0140-6736(10)61965-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21529926 }} </ref><ref name="pmid25057950">{{cite journal| author=Juran BD, Lazaridis KN| title=Environmental factors in primary biliary cirrhosis. | journal=Semin Liver Dis | year= 2014 | volume= 34 | issue= 3 | pages= 265-72 | pmid=25057950 | doi=10.1055/s-0034-1383726 | pmc=4232304 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25057950 }} </ref> | ||
*Few environmental factors such as cigarette smoking, [[infections]] and chemical exposure | *Few environmental factors such as [[cigarette smoking]], [[infections]] and chemical exposure are also known to play a role in causing primary biliary cirrhosis.<ref name="pmid26364546">{{cite journal| author=Carey EJ, Ali AH, Lindor KD| title=Primary biliary cirrhosis. | journal=Lancet | year= 2015 | volume= 386 | issue= 10003 | pages= 1565-75 | pmid=26364546 | doi=10.1016/S0140-6736(15)00154-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26364546 }} </ref><ref name="pmid21529926">{{cite journal| author=Selmi C, Bowlus CL, Gershwin ME, Coppel RL| title=Primary biliary cirrhosis. | journal=Lancet | year= 2011 | volume= 377 | issue= 9777 | pages= 1600-9 | pmid=21529926 | doi=10.1016/S0140-6736(10)61965-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21529926 }} </ref><ref name="pmid25057950">{{cite journal| author=Juran BD, Lazaridis KN| title=Environmental factors in primary biliary cirrhosis. | journal=Semin Liver Dis | year= 2014 | volume= 34 | issue= 3 | pages= 265-72 | pmid=25057950 | doi=10.1055/s-0034-1383726 | pmc=4232304 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25057950 }} </ref> | ||
*To learn more about the risk factors for the development of primary biliary cirrhosis, click '''[[Primary biliary cirrhosis risk factors|here]].''' | *To learn more about the risk factors for the development of primary biliary cirrhosis, click '''[[Primary biliary cirrhosis risk factors|here]].''' | ||
Revision as of 14:16, 15 February 2018
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Primary Biliary Cirrhosis Microchapters |
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Differentiating Primary Biliary Cirrhosis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary biliary cirrhosis causes On the Web |
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American Roentgen Ray Society Images of Primary biliary cirrhosis causes |
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Risk calculators and risk factors for Primary biliary cirrhosis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis. Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing primary biliary cirrhosis.
Causes
- The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis.[1][2][3]
- Few environmental factors such as cigarette smoking, infections and chemical exposure are also known to play a role in causing primary biliary cirrhosis.[1][2][3]
- To learn more about the risk factors for the development of primary biliary cirrhosis, click here.
References
- ↑ 1.0 1.1 Carey EJ, Ali AH, Lindor KD (2015). "Primary biliary cirrhosis". Lancet. 386 (10003): 1565–75. doi:10.1016/S0140-6736(15)00154-3. PMID 26364546.
- ↑ 2.0 2.1 Selmi C, Bowlus CL, Gershwin ME, Coppel RL (2011). "Primary biliary cirrhosis". Lancet. 377 (9777): 1600–9. doi:10.1016/S0140-6736(10)61965-4. PMID 21529926.
- ↑ 3.0 3.1 Juran BD, Lazaridis KN (2014). "Environmental factors in primary biliary cirrhosis". Semin Liver Dis. 34 (3): 265–72. doi:10.1055/s-0034-1383726. PMC 4232304. PMID 25057950.