Primary biliary cirrhosis other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis. Findings on an cholangiography diagnostic of primary biliary cirrhosis include shortened and diminished | Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out [[Primary sclerosing cholangitis|primary sclerosing cholangitis.]] Findings on an cholangiography diagnostic of primary biliary cirrhosis include shortened and diminished branches of the [[intrahepatic bile ducts]]. Transient elastography (Fibroscan) is used to evaluate the extent of fibrosis in advanced disease. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
'''Cholangiography''' | '''Cholangiography''' | ||
*Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis. Findings on an cholangiography diagnostic of primary biliary cirrhosis include:<ref name="pmid5096817">{{cite journal |vauthors=Legge DA, Carlson HC, Dickson ER, Ludwig J |title=Cholangiographic findings in cholangiolitic hepatitis. Syndrome of primary biliary cirrhosis |journal=Am J Roentgenol Radium Ther Nucl Med |volume=113 |issue=1 |pages=16–20 |year=1971 |pmid=5096817 |doi= |url=}}</ref><ref name="LindorGershwin2009">{{cite journal|last1=Lindor|first1=Keith D.|last2=Gershwin|first2=M. Eric|last3=Poupon|first3=Raoul|last4=Kaplan|first4=Marshall|last5=Bergasa|first5=Nora V.|last6=Heathcote|first6=E. Jenny|title=Primary biliary cirrhosis|journal=Hepatology|volume=50|issue=1|year=2009|pages=291–308|issn=02709139|doi=10.1002/hep.22906}}</ref> | *Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis. | ||
**Shortening of intrahepatic bile ducts | *Findings on an cholangiography diagnostic of primary biliary cirrhosis include:<ref name="pmid5096817">{{cite journal |vauthors=Legge DA, Carlson HC, Dickson ER, Ludwig J |title=Cholangiographic findings in cholangiolitic hepatitis. Syndrome of primary biliary cirrhosis |journal=Am J Roentgenol Radium Ther Nucl Med |volume=113 |issue=1 |pages=16–20 |year=1971 |pmid=5096817 |doi= |url=}}</ref><ref name="LindorGershwin2009">{{cite journal|last1=Lindor|first1=Keith D.|last2=Gershwin|first2=M. Eric|last3=Poupon|first3=Raoul|last4=Kaplan|first4=Marshall|last5=Bergasa|first5=Nora V.|last6=Heathcote|first6=E. Jenny|title=Primary biliary cirrhosis|journal=Hepatology|volume=50|issue=1|year=2009|pages=291–308|issn=02709139|doi=10.1002/hep.22906}}</ref> | ||
**Shortening of [[intrahepatic bile ducts]] | |||
**Diminishing of intrahepatic bile ducts | **Diminishing of intrahepatic bile ducts | ||
'''Transient elastography (Fibroscan)''' | '''Transient elastography (Fibroscan)''' | ||
*Findings on transient elastography may show reasonable correlation with the severity of cirrhosis:<ref name="CorpechotEl Naggar2006">{{cite journal|last1=Corpechot|first1=Christophe|last2=El Naggar|first2=Ahmed|last3=Poujol-Robert|first3=Armelle|last4=Ziol|first4=Marianne|last5=Wendum|first5=Dominique|last6=Chazouillères|first6=Olivier|last7=de Lédinghen|first7=Victor|last8=Dhumeaux|first8=Daniel|last9=Marcellin|first9=Patrick|last10=Beaugrand|first10=Michel|last11=Poupon|first11=Raoul|title=Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC|journal=Hepatology|volume=43|issue=5|year=2006|pages=1118–1124|issn=0270-9139|doi=10.1002/hep.21151}}</ref><ref>{{cite journal |author=Foucher J, Chanteloup E, Vergniol J, ''et al'' |title=Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study |journal=Gut |volume=55|issue=3 |pages=403-8 |year=2006 |pmid=16020491 |doi=10.1136/gut.2005.069153}}</ref><ref name="pmid22733854">{{cite journal |author=Xie L, Chen X, Guo Q, Dong Y, Guang Y, Zhang X |title=Real-time elastography for diagnosis of liver fibrosis in chronic hepatitis B |journal=[[Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine]] |volume=31 |issue=7 |pages=1053–60 |year=2012|pmid=22733854 |doi= |url=}}</ref> | *Findings on transient elastography may show reasonable correlation with the severity of [[cirrhosis]]:<ref name="CorpechotEl Naggar2006">{{cite journal|last1=Corpechot|first1=Christophe|last2=El Naggar|first2=Ahmed|last3=Poujol-Robert|first3=Armelle|last4=Ziol|first4=Marianne|last5=Wendum|first5=Dominique|last6=Chazouillères|first6=Olivier|last7=de Lédinghen|first7=Victor|last8=Dhumeaux|first8=Daniel|last9=Marcellin|first9=Patrick|last10=Beaugrand|first10=Michel|last11=Poupon|first11=Raoul|title=Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC|journal=Hepatology|volume=43|issue=5|year=2006|pages=1118–1124|issn=0270-9139|doi=10.1002/hep.21151}}</ref><ref>{{cite journal |author=Foucher J, Chanteloup E, Vergniol J, ''et al'' |title=Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study |journal=Gut |volume=55|issue=3 |pages=403-8 |year=2006 |pmid=16020491 |doi=10.1136/gut.2005.069153}}</ref><ref name="pmid22733854">{{cite journal |author=Xie L, Chen X, Guo Q, Dong Y, Guang Y, Zhang X |title=Real-time elastography for diagnosis of liver fibrosis in chronic hepatitis B |journal=[[Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine]] |volume=31 |issue=7 |pages=1053–60 |year=2012|pmid=22733854 |doi= |url=}}</ref> | ||
** Increasing [[Scar|scarring]] of the [[liver]] is associated with increasing "stiffness" of the [[Tissue (biology)|tissue]]. | ** Increasing [[Scar|scarring]] of the [[liver]] is associated with increasing "stiffness" of the [[Tissue (biology)|tissue]]. | ||
==References== | ==References== | ||
Revision as of 21:37, 7 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis. Findings on an cholangiography diagnostic of primary biliary cirrhosis include shortened and diminished branches of the intrahepatic bile ducts. Transient elastography (Fibroscan) is used to evaluate the extent of fibrosis in advanced disease.
Other Imaging Findings
Cholangiography
- Cholangiography may be helpful for the diagnosis of primary biliary cirrhosis with noninvasive magnetic resonance imaging or endoscopically to rule out primary sclerosing cholangitis.
- Findings on an cholangiography diagnostic of primary biliary cirrhosis include:[1][2]
- Shortening of intrahepatic bile ducts
- Diminishing of intrahepatic bile ducts
Transient elastography (Fibroscan)
- Findings on transient elastography may show reasonable correlation with the severity of cirrhosis:[3][4][5]
References
- ↑ Legge DA, Carlson HC, Dickson ER, Ludwig J (1971). "Cholangiographic findings in cholangiolitic hepatitis. Syndrome of primary biliary cirrhosis". Am J Roentgenol Radium Ther Nucl Med. 113 (1): 16–20. PMID 5096817.
- ↑ Lindor, Keith D.; Gershwin, M. Eric; Poupon, Raoul; Kaplan, Marshall; Bergasa, Nora V.; Heathcote, E. Jenny (2009). "Primary biliary cirrhosis". Hepatology. 50 (1): 291–308. doi:10.1002/hep.22906. ISSN 0270-9139.
- ↑ Corpechot, Christophe; El Naggar, Ahmed; Poujol-Robert, Armelle; Ziol, Marianne; Wendum, Dominique; Chazouillères, Olivier; de Lédinghen, Victor; Dhumeaux, Daniel; Marcellin, Patrick; Beaugrand, Michel; Poupon, Raoul (2006). "Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC". Hepatology. 43 (5): 1118–1124. doi:10.1002/hep.21151. ISSN 0270-9139.
- ↑ Foucher J, Chanteloup E, Vergniol J; et al. (2006). "Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study". Gut. 55 (3): 403–8. doi:10.1136/gut.2005.069153. PMID 16020491.
- ↑ Xie L, Chen X, Guo Q, Dong Y, Guang Y, Zhang X (2012). "Real-time elastography for diagnosis of liver fibrosis in chronic hepatitis B". Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. 31 (7): 1053–60. PMID 22733854.