Eosinophilic pneumonia causes: Difference between revisions
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==== '''Acute eosinophilic pneumonia (AEP)''' ==== | ==== '''Acute eosinophilic pneumonia (AEP)''' ==== | ||
* The cause of acute eosinophilic pneumonia is unknown | * The cause of acute eosinophilic pneumonia is unknown but an acute hypersensitivity reaction is suggested. [1] | ||
'''Chrnoic eosinophilic pneumonia (CEP)''' | '''Chrnoic eosinophilic pneumonia (CEP)''' | ||
* Chronic eosinophilic pneumonia is an idiopathic disorder characterized by an abnormal and marked accumulation of eosinophils in the interstitium and alveolar spaces of the lung. | |||
Chronic eosinophilic pneumonia | |||
==== '''Transpulmonary passage of helminth larvae (Löffler syndrome)''' ==== | ==== '''Transpulmonary passage of helminth larvae (Löffler syndrome)''' ==== | ||
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==== '''Tropical pulmonary eosinophilia''' ==== | ==== '''Tropical pulmonary eosinophilia''' ==== | ||
* Tropical pulmonary eosinophilia is immune response to the bloodborne microfilarial stages of the lymphatic filariae and Wuchereria bancrofti. [16-18]. | * Tropical pulmonary eosinophilia is immune response to the bloodborne microfilarial stages of the lymphatic filariae and Wuchereria bancrofti. [16-18]. | ||
* | * Pulmonary function tests may show a mixed restrictive and obstructive abnormality with a reduction in diffusion capacity. [18] | ||
==== '''Eosinophilic granulomatosis with polyangitis''' ==== | ==== '''Eosinophilic granulomatosis with polyangitis''' ==== | ||
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==== '''Allergic bronchopulmonary aspergillosis''' ==== | ==== '''Allergic bronchopulmonary aspergillosis''' ==== | ||
* Allergic bronchopulmonary aspergillosis | * Allergic bronchopulmonary aspergillosis is a complex hypersensitivity reaction that occurs when airways become colonized by ''Aspergillus.'' [51] | ||
* Immunologic responses elicited by ''Aspergillus fumigatus'' are responsible for this syndrome. It can lead to bronchiectasis, fibrosis, and respiratory compromise. | |||
* Immunologic responses elicited by ''Aspergillus fumigatus'' are responsible for this syndrome. | |||
==== Drugs and toxins ==== | ==== Drugs and toxins ==== |
Revision as of 21:26, 11 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
Causes
Acute eosinophilic pneumonia (AEP)
- The cause of acute eosinophilic pneumonia is unknown but an acute hypersensitivity reaction is suggested. [1]
Chrnoic eosinophilic pneumonia (CEP)
- Chronic eosinophilic pneumonia is an idiopathic disorder characterized by an abnormal and marked accumulation of eosinophils in the interstitium and alveolar spaces of the lung.
Transpulmonary passage of helminth larvae (Löffler syndrome)
- Three types of helminths, Ascaris (A. lumbricoides, A. suum), hookworms (Ancylostoma duodenale, Necator americanus), and Strongyloides stercoralis, have larvae that reach the lungs, penetrate into alveoli, and ascend the airways then reach the gastrointestinal tract. [10]
- Ascaris is the most common cause of Löffler syndrome worldwide. [11]
Tropical pulmonary eosinophilia
- Tropical pulmonary eosinophilia is immune response to the bloodborne microfilarial stages of the lymphatic filariae and Wuchereria bancrofti. [16-18].
- Pulmonary function tests may show a mixed restrictive and obstructive abnormality with a reduction in diffusion capacity. [18]
Eosinophilic granulomatosis with polyangitis
- Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) is a vasculitic disorder often characterized by sinusitis, asthma, and prominent peripheral blood eosinophilia. [49]
- It is the sole form of vasculitis that is associated with both eosinophilia and frequent lung involvement. In addition to the lungs, the skin and the cardiovascular, gastrointestinal, renal, and neurologic systems may also be involved.
Allergic bronchopulmonary aspergillosis
- Allergic bronchopulmonary aspergillosis is a complex hypersensitivity reaction that occurs when airways become colonized by Aspergillus. [51]
- Immunologic responses elicited by Aspergillus fumigatus are responsible for this syndrome. It can lead to bronchiectasis, fibrosis, and respiratory compromise.
Drugs and toxins
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced hypersensitivity reaction that includes skin eruption, eosinophilia, atypical lymphocytosis, lymphadenopathy, and kidney involvement. Drugs causing DRESS are:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) [26]
- anticonvulsants
- antidepressants
- angiotensin converting enzyme inhibitors
- beta blockers
- hydrochlorothiazide
- sulfa-containing compounds [27]