Pancoast tumor natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
*The patient experiences non-specific symptoms such as [[cough]], [[hemoptysis]], [[dyspnea]], [[chest pain]], [[dysphonia]], [[dysphagia]], lack of appetite, [[weight loss]], and [[fatigue]] from 3 weeks to 3 months before seeking medical attention. | |||
*Without treatment, the patient will develop symptoms of cough and chest pain, which may eventually lead to Pancoast syndrome. | |||
==Complications== | ==Complications== | ||
Revision as of 17:14, 21 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]
Natural History
- The patient experiences non-specific symptoms such as cough, hemoptysis, dyspnea, chest pain, dysphonia, dysphagia, lack of appetite, weight loss, and fatigue from 3 weeks to 3 months before seeking medical attention.
- Without treatment, the patient will develop symptoms of cough and chest pain, which may eventually lead to Pancoast syndrome.
Complications
Prognosis
- The prognosis of Pancoast tumor depends on the stage of the tumor at diagnosis.[1][2][3]
- The presence of the following is associated with a poor prognosis among patients with Pancoast tumor :
- Horner syndrome
- Spread to the mediastinal lymph nodes
- Incomplete resection of tumor
- Involvement of supraclavicular lymph node
- Vertebral body invasion
- Metastasis to the brain
- Pancoast tumor is associated with a 5 survival rate as follows depending on the stage of disease:
| Stage Of Pancoast Tumor | 5 year survival rate |
|---|---|
| IIB | 47% |
| IIIA | 14% |
| IIIB | 16% |
References
- ↑ Komaki R, Roth JA, Walsh GL, Putnam JB, Vaporciyan A, Lee JS, Fossella FV, Chasen M, Delclos ME, Cox JD (September 2000). "Outcome predictors for 143 patients with superior sulcus tumors treated by multidisciplinary approach at the University of Texas M. D. Anderson Cancer Center". Int. J. Radiat. Oncol. Biol. Phys. 48 (2): 347–54. PMID 10974447.
- ↑ Ginsberg RJ, Martini N, Zaman M, Armstrong JG, Bains MS, Burt ME, McCormack PM, Rusch VW, Harrison LB (June 1994). "Influence of surgical resection and brachytherapy in the management of superior sulcus tumor". Ann. Thorac. Surg. 57 (6): 1440–5. PMID 8010786.
- ↑ Johnson DE, Goldberg M (June 1997). "Management of carcinoma of the superior pulmonary sulcus". Oncology (Williston Park, N.Y.). 11 (6): 781–5, discussion 785–6. PMID 9189936.