Pancoast tumor causes: Difference between revisions
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==Overview== | |||
Most common cause of Pancoast tumor is non–small cell lung carcinoma (NSCLC).Common types of non-small cell lung carcinoma (NSCLC) presenting as Pancoast tumor are squamous cell cancer, adenocarcinoma and large cell carcinoma. Less common causes of Pancoast tumor includes small cell cancer as it rarely presents as a peripheral tumor. Pancoast syndrome is classically associated with Pancoast tumor. Rare causes of Pancoast syndrome include desmoid tumor, metastasis, hematologic neoplasms, and infections that may present as a tumor localized to the lung apex. | |||
==Causes== | ==Causes== | ||
*Most common cause of Pancoast tumor is non–small cell lung carcinoma (NSCLC).<ref name="pmid24672686">{{cite journal |vauthors=Panagopoulos N, Leivaditis V, Koletsis E, Prokakis C, Alexopoulos P, Baltayiannis N, Hatzimichalis A, Tsakiridis K, Zarogoulidis P, Zarogoulidis K, Katsikogiannis N, Kougioumtzi I, Machairiotis N, Tsiouda T, Kesisis G, Siminelakis S, Madesis A, Dougenis D |title=Pancoast tumors: characteristics and preoperative assessment |journal=J Thorac Dis |volume=6 Suppl 1 |issue= |pages=S108–15 |year=2014 |pmid=24672686 |pmc=3966151 |doi=10.3978/j.issn.2072-1439.2013.12.29 |url=}}</ref><ref name="pmid747642">{{cite journal |vauthors=Jocelyn PC |title=The reduction of diamide by rat liver mitochondria and the role of glutathione |journal=Biochem. J. |volume=176 |issue=3 |pages=649–64 |year=1978 |pmid=747642 |pmc=1186286 |doi= |url=}}</ref><ref name="pmid23702478">{{cite journal |vauthors=Glassman LR, Hyman K |title=Pancoast tumor: a modern perspective on an old problem |journal=Curr Opin Pulm Med |volume=19 |issue=4 |pages=340–3 |year=2013 |pmid=23702478 |doi=10.1097/MCP.0b013e3283621b31 |url=}}</ref><ref name="pmid3754528">{{cite journal |vauthors=Amin R |title=Bilateral Pancoast's syndrome in a patient with carcinoma of the cervix |journal=Gynecol. Oncol. |volume=24 |issue=1 |pages=126–8 |year=1986 |pmid=3754528 |doi= |url=}}</ref><ref name="pmid8153951">{{cite journal |vauthors=Mills PR, Han LY, Dick R, Clarke SW |title=Pancoast syndrome caused by a high grade B cell lymphoma |journal=Thorax |volume=49 |issue=1 |pages=92–3 |year=1994 |pmid=8153951 |pmc=474122 |doi= |url=}}</ref> | *Most common cause of Pancoast tumor is non–small cell lung carcinoma (NSCLC).<ref name="pmid24672686">{{cite journal |vauthors=Panagopoulos N, Leivaditis V, Koletsis E, Prokakis C, Alexopoulos P, Baltayiannis N, Hatzimichalis A, Tsakiridis K, Zarogoulidis P, Zarogoulidis K, Katsikogiannis N, Kougioumtzi I, Machairiotis N, Tsiouda T, Kesisis G, Siminelakis S, Madesis A, Dougenis D |title=Pancoast tumors: characteristics and preoperative assessment |journal=J Thorac Dis |volume=6 Suppl 1 |issue= |pages=S108–15 |year=2014 |pmid=24672686 |pmc=3966151 |doi=10.3978/j.issn.2072-1439.2013.12.29 |url=}}</ref><ref name="pmid747642">{{cite journal |vauthors=Jocelyn PC |title=The reduction of diamide by rat liver mitochondria and the role of glutathione |journal=Biochem. J. |volume=176 |issue=3 |pages=649–64 |year=1978 |pmid=747642 |pmc=1186286 |doi= |url=}}</ref><ref name="pmid23702478">{{cite journal |vauthors=Glassman LR, Hyman K |title=Pancoast tumor: a modern perspective on an old problem |journal=Curr Opin Pulm Med |volume=19 |issue=4 |pages=340–3 |year=2013 |pmid=23702478 |doi=10.1097/MCP.0b013e3283621b31 |url=}}</ref><ref name="pmid3754528">{{cite journal |vauthors=Amin R |title=Bilateral Pancoast's syndrome in a patient with carcinoma of the cervix |journal=Gynecol. Oncol. |volume=24 |issue=1 |pages=126–8 |year=1986 |pmid=3754528 |doi= |url=}}</ref><ref name="pmid8153951">{{cite journal |vauthors=Mills PR, Han LY, Dick R, Clarke SW |title=Pancoast syndrome caused by a high grade B cell lymphoma |journal=Thorax |volume=49 |issue=1 |pages=92–3 |year=1994 |pmid=8153951 |pmc=474122 |doi= |url=}}</ref> | ||
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**Adenoid cystic carcinoma | **Adenoid cystic carcinoma | ||
**Lymphoma | **Lymphoma | ||
**Vascular aneurysms | **Vascular aneurysms | ||
**Cervical rib syndrome | **Cervical rib syndrome | ||
Revision as of 16:18, 26 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]
Overview
Most common cause of Pancoast tumor is non–small cell lung carcinoma (NSCLC).Common types of non-small cell lung carcinoma (NSCLC) presenting as Pancoast tumor are squamous cell cancer, adenocarcinoma and large cell carcinoma. Less common causes of Pancoast tumor includes small cell cancer as it rarely presents as a peripheral tumor. Pancoast syndrome is classically associated with Pancoast tumor. Rare causes of Pancoast syndrome include desmoid tumor, metastasis, hematologic neoplasms, and infections that may present as a tumor localized to the lung apex.
Causes
- Most common cause of Pancoast tumor is non–small cell lung carcinoma (NSCLC).[1][2][3][4][5]
- Common types of non-small cell lung carcinoma (NSCLC) presenting as Pancoast tumor are squamous cell cancer, adenocarcinoma and large cell carcinoma.
- Less common causes of Pancoast tumor includes small cell cancer as it rarely presents as a peripheral tumor.
- Pancoast syndrome is classically associated with Pancoast tumor.
- Rare causes of Pancoast syndrome include:[6][7][8][9][10]
- Desmoid tumor-intrathoracic fibromatosis
- Metastatic spread from:
- Carcinoma of larynx
- Carcinoma of cervix
- Carcinoma of urinary bladder
- Carcinoma of thyroid gland
- Hematologic neoplasms:
- Plasmacytoma
- Lymphomatoid granulomatosis
- Lymphoma
- Amyloidoma
- Infections such as:
- Bacterial
- Staphylococcal pneumonia
- Pseudomonal pneumonia
- Thoracic actinomycosis
- Fungal
- Aspergillosis
- Allescheriasis
- Cryptococcosis
- Bacterial
- Hemangiopericytoma
- Adenoid cystic carcinoma
- Lymphoma
- Vascular aneurysms
- Cervical rib syndrome
- Mycotic subclavian artery aneurysm
- Hydatid cyst presenting as carotid pseudoaneurysm
References
- ↑ Panagopoulos N, Leivaditis V, Koletsis E, Prokakis C, Alexopoulos P, Baltayiannis N, Hatzimichalis A, Tsakiridis K, Zarogoulidis P, Zarogoulidis K, Katsikogiannis N, Kougioumtzi I, Machairiotis N, Tsiouda T, Kesisis G, Siminelakis S, Madesis A, Dougenis D (2014). "Pancoast tumors: characteristics and preoperative assessment". J Thorac Dis. 6 Suppl 1: S108–15. doi:10.3978/j.issn.2072-1439.2013.12.29. PMC 3966151. PMID 24672686.
- ↑ Jocelyn PC (1978). "The reduction of diamide by rat liver mitochondria and the role of glutathione". Biochem. J. 176 (3): 649–64. PMC 1186286. PMID 747642.
- ↑ Glassman LR, Hyman K (2013). "Pancoast tumor: a modern perspective on an old problem". Curr Opin Pulm Med. 19 (4): 340–3. doi:10.1097/MCP.0b013e3283621b31. PMID 23702478.
- ↑ Amin R (1986). "Bilateral Pancoast's syndrome in a patient with carcinoma of the cervix". Gynecol. Oncol. 24 (1): 126–8. PMID 3754528.
- ↑ Mills PR, Han LY, Dick R, Clarke SW (1994). "Pancoast syndrome caused by a high grade B cell lymphoma". Thorax. 49 (1): 92–3. PMC 474122. PMID 8153951.
- ↑ "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 18-2000. A 45-year-old woman with a thoracic mass and Pancoast's syndrome". N. Engl. J. Med. 342 (24): 1814–21. 2000. doi:10.1056/NEJM200006153422408. PMID 10853005.
- ↑ Chong KM, Hennox SC, Sheppard MN (1993). "Primary hemangiopericytoma presenting as a Pancoast tumor". Ann. Thorac. Surg. 55 (2): 9. PMID 8431033.
- ↑ Hatton MQ, Allen MB, Cooke NJ (1993). "Pancoast syndrome: an unusual presentation of adenoid cystic carcinoma". Eur. Respir. J. 6 (2): 271–2. PMID 8383065.
- ↑ Vandenplas O, Mercenier C, Trigaux JP, Delaunois L (1991). "Pancoast's syndrome due to Pseudomonas aeruginosa infection of the lung apex". Thorax. 46 (9): 683–4. PMC 463373. PMID 1948800.
- ↑ Gallagher KJ, Jeffrey RR, Kerr KM, Steven MM (1992). "Pancoast syndrome: an unusual complication of pulmonary infection by Staphylococcus aureus". Ann. Thorac. Surg. 53 (5): 903–4. PMID 1570995.