Differentiating Temporal arteritis from other diseases: Difference between revisions
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! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Biopsy]] | ! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Biopsy]] | ||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Jaw pain]] and [[Jaw claudication|claudication]] | ! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Jaw pain]] and [[Jaw claudication|claudication]] | ||
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! colspan="2" style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Polymyalgia rheumatica|Polymyalgia rheumatica (PMR)]]<ref name="pmid18390527">{{cite journal| author=Michet CJ, Matteson EL| title=Polymyalgia rheumatica. | journal=BMJ | year= 2008 | volume= 336 | issue= 7647 | pages= 765-9 | pmid=18390527 | doi=10.1136/bmj.39514.653588.80 | pmc=2287267 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18390527 }}</ref> | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+ | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+ | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Fibrinogen|Plasma fibrinogen]] | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Normocytic normochromic anemia|Normocytic, normochromic anemia]] | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑ | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[CRP]] | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Odontoid process|Periodontoid]] localization of [[calcification]] | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Vessel wall]] thickening, Increased mural contrast enhancement | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Subacromial bursitis|Subacromial]] or subdeltoid [[bursitis]] | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |High [[Fluorescein sodium|F-FDG]] accumulation around the [[joints]] in [[Positron emission tomography|FDG PET-CT]] | |||
!Small angular fibers, [[Pyknosis|Pyknotic]] [[nuclear]] clumps, or target-targetoid fibers | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |- | |||
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Joint stiffness]], [[Fatigue]] | |||
==References== | ==References== | ||
Revision as of 01:55, 5 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Temporal Arteritis from other Diseases
The following list is a differential diagnosis of disorders that temporal arteritis should be distinguished from.
- Cluster headache
- Migraine headache
- Multi-infarct dementia
- Persistent idiopathic facial pain
- Polyarteritis nodosa
- Postherpetic neuralgia
- Sinusitis
- Trigeminal neuralgia
- Stroke
- Wegener granulomatosis
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Physical examination | ||||||||||||||||||||
| Lab Findings | Imaging | Histopathology | |||||||||||||||||||
| Headache | Fever | Weight loss | Arthralgia | Claudication | Bruit | HTN | Focal neurological disorder | Biomarker | CBC | ESR | Other | CT scan | Angiography | Ultrasound/ Echocardiography | Other | ||||||
| Large-Vessel Vasculitis | Takayasu arteritis[1] | + | +/- | + | - | + | + | +/- | +/- | MMP-3 and MMP-9 | Leukocytosis, Anemia | ↑ | ↑CRP | Aneurysmal dilatation of the aorta | Blood vessel stenosis | Circumferential thickening of the arterial wall (Macaroni sign) | PET-scan, Cardiac CT | Granulomatous inflammation of arteries | Arteriography | Coronary aneurysm | |
| Giant cell arteritis[2] | + | - | + | +/- | - | - | - | +/- | Pentraxin 3 (PTX3) | Normal | ↑ | ↑CRP | Stenosis, Occlusion, Dilatation | Aneurysm | - | Mural inflammation in MRA | Granulomatous inflammation of arteries | Biopsy | Jaw pain and claudication | ||
| Polymyalgia rheumatica (PMR)[3] | + | - | +/- | + | - | - | - | - | Plasma fibrinogen | Normocytic, normochromic anemia | ↑ | CRP | Periodontoid localization of calcification | Vessel wall thickening, Increased mural contrast enhancement | Subacromial or subdeltoid bursitis | High F-FDG accumulation around the joints in FDG PET-CT | Small angular fibers, Pyknotic nuclear clumps, or target-targetoid fibers | - | Joint stiffness, Fatigue
References
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